Scopus
YÖKSİS Eşleşti
Salvia nemorosa L.: A novel source of bioactive agents with functional connections
LWT · Ocak 2017
YÖKSİS Kayıtları
Salvia nemorosa L.: A novel source of bioactive agents with functional connections
LWT - Food Science and Technology · 2017 SCI-Expanded
PROFESÖR GÖKHAN ZENGİN →
Makale Bilgileri
DergiLWT
Yayın TarihiOcak 2017
Cilt / Sayfa75 · 42-50
Scopus ID2-s2.0-84983554887
Özet
Salvia species are used as food and medicinal plants all around the world. In this study, chemical composition and antimicrobial, toxicity, antioxidant, and enzyme inhibitory activity of Salvia nemorosa were evaluated. Phenolic components were characterized by the HPLC-DAD and 11 components were identified, in which rosmarinic acid was detected as the major compound (7584 μg/g extract). Sixteen volatile components were determined in both leaves and flowers essential oils. Oxygenated sesquiterpenes were the major components. Methanolic extract showed the highest total phenolic and flavonoid contents (294 mg GAE/g and 117 mg QE/g extract, respectively) and the strongest DPPH radical scavenging activity (IC50: 82 μg/mL). Plant samples showed moderate to high aldehyde oxidase, xanthine oxidase, acetylcholinesterase, and α-glucosidase inhibitory activity and moderate cytotoxicity. Also, EOs exhibited great antimicrobial potential (IZ: 8.8–33.7 mm). Our findings indicated that S. nemorosa may be useful for novel applications in functional food and pharmaceutical industries.
Yazarlar (7)
1
Mir Babak Bahadori
2
Behvar Asghari
3
Leila Dinparast
4
Gokhan Zengin
ORCID: 0000-0001-6548-7823
5
Cengiz Sarikurkcu
6
Mahdi Abbas-Mohammadi
7
Shahram Bahadori
Anahtar Kelimeler
Acetylcholinesterase
Alzheimer's disease
Diabetes mellitus
Phenolics
Salvia
Kurumlar
Biotechnology Research Center,Tabriz
Tabriz Iran
Imam Khomeini International University
Qazvin Iran
Research Center for Pharmaceutical Nanotechnology
Tabriz Iran
Selçuk Üniversitesi
Selçuklu Turkey
Shahid Beheshti University
Tehran Iran
Süleyman Demirel Üniversitesi
Isparta Turkey
Urmia University of Medical Sciences
Urmia Iran
Metrikler
59
Atıf
7
Yazar
5
Anahtar Kelime