Filament winding and roll wrapping methods are widely used in the production of composite tubes. While the mechanical behavior of composites produced by different methods may be different, the effects of the damages that occurred while machining composite tubes on the mechanical behavior may also be different. In this study, the effects of drilling-induced damages and hole quality on the tensile and fatigue strength of the filament-wound and roll-wrapped composite tubes were experimentally investigated. Results showed that while the behavior of the filament-wound composite tube under hoop tensile load is better than the roll-wrapped composite tube, the roll-wrapped tube performs better than filament-wound tube under hoop fatigue load. It was also observed that different drilling conditions affect the mechanical behavior of filament-wound tube while it was found that drilling conditions do not have a significant effect on the mechanical behavior of roll-wrapped tube because manufacturing defects are more dominant.