Scopus Eşleşmesi Bulundu
121
Atıf
218
Cilt
Scopus Yazarları: Vanessa Sancho-Shimizu, Elie Haddad, Marta Gut, Jacques G. Rivière, Pere Soler-Palacin, Melike Emiroglu, Sefika Elmas Bozdemir, Esra Akyuz Ozkan, Hulya Vatansev, Selda Hancerli Torun, Taner Coskuner, Yasemin Kendir Demirkol, Esra Sevketoglu, Isabelle Meyts, Laura Marque, João Farela Neves, Alessandro Aiuti, Ahmed A. Bousfiha, Ali Sobh, Fanny Bajolle, Damien Bonnet, Weite Lei, Dusan Bogunovic, Shen Ying Zhang, Rebeca Pérez de Diego, Laia Alsina, Daniel Blazquez-Gamero, Sevgi Keles, Sadiye Kubra Tuter Oz, Aslinur Ozkaya Parlakay, Adem Karbuz, Gokhan Aytekin, Hasan Kapakli, Volkan Yarar, Alper Yosunkaya, Serdar Nepesov, Adam Klocperk, Levi Hoste, Antonio Novelli, Majistor Maglorius, Quentin Philippot, Simon J. Pelham, Aurélie Cobat, Carrie L. Lucas, Sarah E. Henrickson, Stuart G. Tangye, Michael Levin, Kathie Beland, Aurora Pujol, Agatha Schlüter, Laura Planas-Serra, Juan Valencia-Ramos, Agusti Rodriguez-Palmero, Roger Colobran, Gulsum Alkan, Selma Erol Aytekin, Yahya Gul, Saliha Kanik-Yuksek, Belgin Gulhan, Aysun Yahsi, Ahmet Osman Kilic, Emine Hafize Erdeniz, Zerrin Orbak, Şehnaz Aydemir, Bahar Kandemir, Betul Sözeri, Ozgur Kasapcopur, Osman Yesilbas, Zeynep Gökçe Gayretli Aydın, Anna Sediva, Selket Delafontaine, Filomeen Haerynck, Mohammad Shahrooei, Saleh Zaid Almuhsen, Alenka Gagro, Pierre Lebon, Danyel Lee, Peng Zhang, Petter Brodin, Catherine M. Biggs, Julie Toubiana, Alexandre Belot, Joshua D. Milner, Laurent Abel, Jean Laurent Casanova, Sergio Aguilera-Albesa, Carlos Rodriguez-Gallego, Carlos Flores, Iolanda Jordan, Özge Metin Akcan, Gulsum Iclal Bayhan, Jale Çelik, Caner Aytekin, Mehmet Yıldız, Nevin Hatipoglu, Tayfun Ozcelik, Marketa Bloomfield, Giuseppe Novelli, Giorgio Casari, Yoann Seeleuthner
Özet
Multisystem inflammatory syndrome in children (MIS-C) emerged in April 2020 in communities with high COVID-19 rates. This new condition is heterogenous but resembles Kawasaki disease (KD), a well-known but poorly understood and clinically heterogenous pediatric inflammatory condition for which weak associations have been found with a myriad of viral illnesses. Epidemiological data clearly indicate that SARS-CoV-2 is the trigger for MIS-C, which typically occurs about 1 mo after infection. These findings support the hypothesis of viral triggers for the various forms of classic KD. We further suggest that rare inborn errors of immunity (IEIs) altering the immune response to SARS-CoV-2 may underlie the pathogenesis of MIS-C in some children. The discovery of monogenic IEIs underlying MIS-C would shed light on its pathogenesis, paving the way for a new genetic approach to classic KD, revisited as a heterogeneous collection of IEIs to viruses.
Makale Bilgileri
Dergi
Journal of Experimental Medicine
ISSN
0022-1007
Yıl
2021
/ 1. ay
Cilt / Sayı
218
Makale Türü
Derleme Makale
Hakemlik
Hakemli
Endeks
SCI-Expanded
JCR Quartile
Q1
Yayın Dili
Türkçe
Kapsam
Uluslararası
Toplam Yazar
16 kişi
Erişim Türü
Elektronik
Erişim Linki
Makaleye Git
Alan
Sağlık Bilimleri Temel Alanı
Çocuk Enfeksiyon Hastalıkları
YÖKSİS Yazar Kaydı
Yazar Adı
Sancho-Shimizu Vanessa, Brodin Petter, Cobat Aurélie, M Biggs Catherine M, Toubiana Julie, Lucas Carrie L, Henrickson Sarah E, Belot Alexandre, EMİROĞLU MELİKE, Tangye Stuart G, Milner Joshua D, Levin Michael, Abel Laurent, Bogunovic Dusan, Casanova Jean-Laurent, Zhang Shen-Ying
YÖKSİS ID
5623119
Hızlı Erişim
Metrikler
Scopus Atıf
121
JCR Quartile
Q1
Yazar Sayısı
16