Scopus
YÖKSİS Eşleşti
SARS-CoV-2-related MIS-C: A key to the viral and genetic causes of Kawasaki disease?
Journal of Experimental Medicine · Nisan 2021
YÖKSİS Kayıtları
SARS-CoV-2–related MIS-C: A key to the viral and genetic causes of Kawasaki disease?
Journal of Experimental Medicine · 2021 SCI-Expanded
DOÇENT GÜLSÜM ALKAN →
SARS-CoV-2–related MIS-C: A key to the viral and genetic causes of Kawasaki disease?
Journal of Experimental Medicine · 2021 SCI-Expanded
PROFESÖR JALE BENGİ ÇELİK →
SARS-CoV-2–related MIS-C: A key to the viral and genetic causes of Kawasaki disease?
Journal of Experimental Medicine · 2021 SCI-Expanded
DOÇENT GÜLSÜM ALKAN →
SARS-CoV-2–related MIS-C: A key to the viral and genetic causes of Kawasaki disease?
Journal of Experimental Medicine · 2021 SCI-Expanded
PROFESÖR JALE BENGİ ÇELİK →
SARS-CoV-2–related MIS-C: A key to the viral and genetic causes of Kawasaki disease?
Journal of Experimental Medicine · 2021 SCI-Expanded
DOÇENT MELİKE EMİROĞLU →
SARS-CoV-2\u2013related MIS-C: A key to the viral and genetic causes of Kawasaki disease?
Journal of Experimental Medicine · 2021 SCI-Expanded
DOÇENT MELİKE EMİROĞLU →
Makale Bilgileri
DergiJournal of Experimental Medicine
Yayın TarihiNisan 2021
Cilt / Sayfa218
Scopus ID2-s2.0-85105542114
Özet
Multisystem inflammatory syndrome in children (MIS-C) emerged in April 2020 in communities with high COVID-19 rates. This new condition is heterogenous but resembles Kawasaki disease (KD), a well-known but poorly understood and clinically heterogenous pediatric inflammatory condition for which weak associations have been found with a myriad of viral illnesses. Epidemiological data clearly indicate that SARS-CoV-2 is the trigger for MIS-C, which typically occurs about 1 mo after infection. These findings support the hypothesis of viral triggers for the various forms of classic KD. We further suggest that rare inborn errors of immunity (IEIs) altering the immune response to SARS-CoV-2 may underlie the pathogenesis of MIS-C in some children. The discovery of monogenic IEIs underlying MIS-C would shed light on its pathogenesis, paving the way for a new genetic approach to classic KD, revisited as a heterogeneous collection of IEIs to viruses.
Yazarlar (100)
1
Vanessa Sancho-Shimizu
ORCID: 0000-0002-3519-0727
2
Petter Brodin
3
Aurélie Cobat
ORCID: 0000-0001-7209-6257
4
Catherine M. Biggs
5
Julie Toubiana
ORCID: 0000-0001-9561-669X
6
Carrie L. Lucas
7
Sarah E. Henrickson
8
Alexandre Belot
ORCID: 0000-0003-4902-5332
9
Stuart G. Tangye
10
Joshua D. Milner
11
Michael Levin
ORCID: 0000-0003-2767-6919
12
Laurent Abel
ORCID: 0000-0001-7016-6493
13
Dusan Bogunovic
14
Jean Laurent Casanova
ORCID: 0000-0002-7782-4169
15
Shen Ying Zhang
ORCID: 0000-0002-9449-3672
16
Elie Haddad
ORCID: 0000-0003-2446-6879
17
Kathie Beland
18
Aurora Pujol
ORCID: 0000-0002-9606-0600
19
Agatha Schlüter
20
Laura Planas-Serra
21
Sergio Aguilera-Albesa
22
Juan Valencia-Ramos
23
Agusti Rodriguez-Palmero
ORCID: 0000-0002-4141-5515
24
Marta Gut
25
Jacques G. Rivière
26
Roger Colobran
27
Pere Soler-Palacin
28
Carlos Rodriguez-Gallego
29
Rebeca Pérez de Diego
ORCID: 0000-0001-8426-8765
30
Carlos Flores
31
Laia Alsina
32
Daniel Blazquez-Gamero
33
Iolanda Jordan
34
Sevgi Keles
35
Melike Emiroglu
ORCID: 0000-0003-1307-0246
36
Özge Metin Akcan
ORCID: 0000-0002-3465-6994
37
Gulsum Alkan
ORCID: 0000-0003-3384-769X
38
Selma Erol Aytekin
39
Yahya Gul
40
Sadiye Kubra Tuter Oz
ORCID: 0000-0002-2473-5672
41
Sefika Elmas Bozdemir
ORCID: 0000-0003-1058-0320
42
Gulsum Iclal Bayhan
ORCID: 0000-0002-1423-4348
43
Saliha Kanik-Yuksek
ORCID: 0000-0002-2538-2872
44
Aslinur Ozkaya Parlakay
45
Belgin Gulhan
ORCID: 0000-0003-0839-1301
46
Aysun Yahsi
47
Ahmet Osman Kilic
48
Adem Karbuz
49
Emine Hafize Erdeniz
50
Esra Akyuz Ozkan
51
Zerrin Orbak
52
Şehnaz Aydemir
53
Jale Çelik
54
Bahar Kandemir
ORCID: 0000-0002-9815-8767
55
Gokhan Aytekin
56
Hasan Kapakli
57
Volkan Yarar
58
Alper Yosunkaya
59
Hulya Vatansev
60
Caner Aytekin
61
Selda Hancerli Torun
62
Serdar Nepesov
63
Taner Coskuner
ORCID: 0000-0001-7844-3387
64
Betul Sözeri
ORCID: 0000-0002-5079-5644
65
Yasemin Kendir Demirkol
66
Ozgur Kasapcopur
67
Mehmet Yıldız
68
Esra Sevketoglu
69
Nevin Hatipoglu
70
Tayfun Ozcelik
ORCID: 0000-0001-5937-1082
71
Osman Yesilbas
72
Zeynep Gökçe Gayretli Aydın
73
Anna Sediva
74
Adam Klocperk
75
Marketa Bloomfield
ORCID: 0000-0001-5330-9341
76
Isabelle Meyts
77
Selket Delafontaine
78
Filomeen Haerynck
ORCID: 0000-0001-9161-7361
79
Levi Hoste
80
Mohammad Shahrooei
81
Laura Marque
82
João Farela Neves
83
Giuseppe Novelli
84
Antonio Novelli
85
Alessandro Aiuti
86
Giorgio Casari
87
Ahmed A. Bousfiha
88
Saleh Zaid Almuhsen
89
Ali Sobh
90
Alenka Gagro
91
Fanny Bajolle
92
Damien Bonnet
93
Pierre Lebon
94
Weite Lei
95
Danyel Lee
ORCID: 0000-0003-3124-0245
96
Yoann Seeleuthner
ORCID: 0000-0002-1878-8567
97
Peng Zhang
98
Majistor Maglorius
99
Quentin Philippot
100
Simon J. Pelham
Kurumlar
Ankara City Hospital
Ankara Turkey
Ankara Yildirim Beyazit University
Ankara Turkey
Atatürk Üniversitesi
Erzurum Turkey
Balıkesir Atatürk City Hospital
Balikesir Turkey
BC Children's Hospital Research Institute
Vancouver Canada
Bilkent Üniversitesi
Ankara Turkey
Bursa City Hospital
Bursa Türkiye
CEDOC
Lisbon Portugal
Centro de Investigación Biomédica en Red de Enfermedades Respiratorias
Madrid Spain
Centro de Regulacion Genomica, Barcelona
Barcelona Spain
Centro Hospitalar Universitário de Santo António
Porto Portugal
Charles University
Prague Czech Republic
Childern's Hospital Zagreb
Zagreb Croatia
CHU de Lyon
Lyon France
CHU Sainte-Justine - Le Centre Hospitalier Universitaire Mère-Enfant
Montreal Canada
Columbia University
New York United States
Complejo Asistencial Universitario de Burgos
Burgos Spain
Departement Microbiologie, Immunologie en Transplantatie
Leuven Belgium
Dr Ali Kemal Belviranli Hospital for Obstetrics and Pediatrics
Konya Turkey
Dr. Sami Ulus Maternity and Children's Health and Diseases Training and Research Hospital
Ankara Turkey
Fakultní Nemocnice v Motole
Prague Czech Republic
Garvan Institute of Medical Research
Sydney Australia
Hassan II University of Casablanca
Casablanca Morocco
Hôpital Necker Enfants Malades
Paris France
Hospital de Dona Estefânia
Lisbon Portugal
Hospital de Gran Canaria Dr. Negrin
Las Palmas de Gran Canaria Spain
Hospital Duran i Reynals
Barcelona Spain
Hospital Sant Joan de Déu Barcelona
Esplugues de Llobregat Spain
Hospital Universitari Germans Trias i Pujol
Badalona Spain
Hospital Universitario La Paz
Madrid Spain
Hospital Universitario Nuestra Senora de Candelaria
Santa Cruz de Tenerife Spain
Howard Hughes Medical Institute
Chevy Chase United States
Icahn School of Medicine at Mount Sinai
New York United States
Imperial College Faculty of Medicine
London United Kingdom
Imperial College London
London United Kingdom
Inserm
Paris France
Institució Catalana de Recerca i Estudis Avançats
Barcelona Spain
Instituto de Investigación Hospital 12 de Octubre
Madrid Spain
Instituto de Salud Carlos III
Madrid Spain
Instituto Tecnológico y de Energías Renovables, S.A.
Granadilla de Abona Spain
Institut Pasteur, Paris
Paris France
Interdepartmental Group of Immunodeficiencies
Madrid Spain
IRCCS Ospedale Pediatrico Bambino Gesù
Rome Italy
İstanbul Medipol Üniversitesi
Istanbul Turkey
İstanbul Tıp Fakültesi
Istanbul Turkey
İstanbul University-Cerrahpaşa Cerrahpaşa Faculty of Medicine
Istanbul Turkey
Josip Juraj Strossmayer University of Osijek Faculty of Medicine
Osijek Croatia
Karadeniz Teknik Üniversitesi Tip Fakültesi
Trabzon Turkey
Karolinska Institutet
Stockholm Sweden
King Saud University
Riyadh Saudi Arabia
Konya City Hospital
Konya Turkey
KU Leuven– University Hospital Leuven
Leuven Belgium
Mansoura University Children's Hospital
Mansoura Egypt
Navarra Health Service Hospital
Pamplona Spain
Necmettin Erbakan Üniversitesi
Meram Turkey
Ondokuz Mayis Üniversitesi
Samsun Turkey
Prof. Dr. Cemil Tascioglu City Hospital
Istanbul Turkey
Rockefeller University
New York United States
Selçuk Tip Fakültesi
Konya Turkey
Selçuk Üniversitesi
Selçuklu Turkey
The Children's Hospital of Philadelphia
Philadelphia United States
The University of British Columbia
Vancouver Canada
Universidad de la Laguna
San Cristobal de La Laguna Spain
Universidad Fernando Pessoa Canarias
Santa Maria de Guia de Gran Canaria Spain
Università degli Studi di Roma "Tor Vergata"
Rome Italy
Universitair Ziekenhuis Gent
Ghent Belgium
Universitat Autònoma de Barcelona
Cerdanyola del Valles Spain
Università Vita-Salute San Raffaele
Milan Italy
Université Claude Bernard Lyon 1
Villeurbanne France
Université Paris Cité
Paris France
University of Health Sciences
Istanbul Turkey
University of Pennsylvania Perelman School of Medicine
Philadelphia United States
UNSW Medicine
Kensington Australia
Yale School of Medicine
New Haven United States
Metrikler
121
Atıf
100
Yazar