Many bedding materials have been tested in broiler industry for their suitability. However, little knowledge is available regarding the usage of different bedding materials supplemented with sepiolite and their effects on animal performance and final product quality. For this purpose, a total of 288 day-old male broiler chicks were randomly allocated into two types of bedding materials (wood shavings and rice hulls). Each bedding material group was divided into 3 subgroups: control with 0% sepiolite, 25%-sepiolite group, and 50%-sepiolite group. Each sub-group was placed in 6 pens with 8 chicks per pen. The effects of bedding materials and sepiolite additions on slaughter yields and some meat quality parameters in broilers were evaluated. Slaughter parameters including hot carcass yield and relative weights of thigh and breast meat, heart, liver, gizzard and bursa Fabricius in broilers were not affected by bedding materials and sepiolite additions (P > 0.05). Also, no significant differences were observed among experimental groups for cooking loss and nutritional profile of breast and thigh meat of broilers (P > 0.05). The freshly measured pH0 of breast and thigh meats was significantly affected by the bedding material and was higher for wood shavings group (P < 0.01). Breast and thigh meats of broilers reared on rice hulls were lighter (P < 0.01), less red, and less yellow in color than those reared on wood shavings, whereas no effect of sepiolite additions was observed on the color of both meat cuts. No substantial effect of bedding material and sepiolite additions was observed on white stripping; however, their occurrence rate found was very high for meat of broilers reared on rice hulls than those reared on wood shavings (P > 0.05). In conclusion, broilers reared on either wood shavings or rice hulls with or without sepiolite additions did not show any negative effects on slaughter yields and meat quality parameters. Furthermore, sepiolite can be an option as a bedding material for broiler industry, but further research with thorough economic analysis is required.