Scopus Eşleşmesi Bulundu
45
Atıf
15
Cilt
🔓
Açık Erişim
Scopus Yazarları: Hatice Türk Dağı, Ugur Arslan, Duygu Findik, Cigdem Senkeles
Özet
Background: In this study, our aim was to identify Candida species isolated from bloodstream infections and to determine their susceptibilities to various antifungal agents to demonstrate the local resistance profiles and to guide empirical treatment for clinicians. Methods: Two hundred Candida isolates (95Candida albicans, 105 non-albicans Candida strains) were included in the study. Candida species were identified by conventional, biochemical and molecular methods. Antifungal susceptibility tests for amphotericin B, fluconazole, voriconazole, posaconazole, caspofungin and anidulafungin were performed with broth microdilution method according to the Clinical and Laboratory Standards Institute M27-A3 document. Results: Of the 200 Candida strains, the most prevalent species were C. albicans (47.5%), Candida glabrata (18.0%) and Candida parapsilosis complex (14.0%). All Candida species except for three (1.5%) Candida kefyr strains were susceptible to amphotericin B. Only one (2.8%) C. glabrata was resistant to fluconazole (MIC ≥ 64 μg/ml), and the others (97.2%) exhibited dose-dependent susceptibility. All species, but C. glabrata strains, were susceptible to fluconazole. Resistance to voriconazole, posaconazole, caspofungin and anidulafungin was not detected in any strain. Conclusion:Candida albicans were susceptible to all antifungal drugs. Three C. kefyr strains were resistant to amphotericin B. Only one C. glabrata was resistant to fluconazole. All the strains were susceptible to voriconazole, posaconazole, caspofungin and anidulafungin. In vitro antifungal susceptibility tests should be performed to select of appropriate and effective antifungal therapy, and monitor the development of resistance.
Anahtar Kelimeler (Scopus)
Anti-fungal susceptibility
Candida
Microdilution method
Scimago Dergi Bilgisi
Otomatik ISSN Eşleştirmesi
2016 yılı verileri
Annals of Clinical Microbiology and Antimicrobials
Q1
SJR Quartile
1,042
SJR Skoru
75
H-Index
🔓
Açık Erişim
Kategoriler: Medicine (miscellaneous) (Q1) · Infectious Diseases (Q2) · Microbiology (medical) (Q2)
Alanlar: Medicine
Ülke: United Kingdom
· BioMed Central Ltd
Bu bilgiler makale yılına göre Scimago veritabanından ISSN eşleştirmesiyle otomatik getirilmektedir.
Dergi sıralama verileri Scimago'nun ilgili yılı baz alınmaktadır.
Anahtar Kelimeler
Anti-fungal susceptibility
Candida
Microdilution method
Makale Bilgileri
Dergi
Annals of Clinical Microbiology and Antimicrobials
ISSN
1476-0711
Yıl
2016
/ 12. ay
Cilt / Sayı
15
/ 1
Makale Türü
Özgün Makale
Hakemlik
Hakemli
Endeks
SCI-Expanded
TEŞV Puanı
18,00
Yayın Dili
İngilizce
Kapsam
Uluslararası
Toplam Yazar
4 kişi
Erişim Türü
Elektronik
Erişim Linki
Makaleye Git
Alan
Sağlık Bilimleri Temel Alanı-
Tıbbi Mikrobiyoloji
YÖKSİS Yazar Kaydı
Yazar Adı
TÜRK DAĞI HATİCE,FINDIK DUYGU,ŞENKELEŞ ÇİĞDEM,ARSLAN UĞUR
YÖKSİS ID
1743155
Hızlı Erişim
Metrikler
Scopus Atıf
45
TEŞV Puanı
18,00
Yazar Sayısı
4