Scopus
Hepatoprotective effect of Foeniculum vulgare essential oil: A carbon-tetrachloride induced liver fibrosis model in rats
Scandinavian Journal of Laboratory Animal Science · Nisan 2004
Makale Bilgileri
DergiScandinavian Journal of Laboratory Animal Science
Yayın TarihiNisan 2004
Cilt / Sayfa31 · 9-17
Scopus ID2-s2.0-17144453632
Özet
Hepatoprotective activity of Foeniculum vulgare (fennel) essential oil was studied using a carbon tetrachloride-induced liver fibrosis model in rats. The hepatotoxicity produced by chronic carbon tetrachloride administration was found to be inhibited by Foeniculum vulgare essential oil with evidence of decreased levels of serum aspartate aminotransferase, alanine aminotransferase, alkaline phosphatase and bilirubin. Histopathological findings also suggest that Foeniculum vulgare essential oil prevents the development of chronic liver damage. The changes in body weights in the rats assigned to the study groups supported these biochemical and histopathological findings. The results of this study clearly indicate that Foeniculum vulgare essential oil has a potent hepatoprotective action against carbon tetrachloride-induced liver fibrosis in rats.
Yazarlar (7)
1
Hanefi Özbek
2
Serdar Uğraş
3
Irfan Bayram
4
Ismail Uygan
5
Ender Erdoğan
6
Abdurrahman Öztürk
7
Zübeyir Huyut
Anahtar Kelimeler
Carbon tetrachloride
Fennel essential oil
FEO
Foeniculum vulgare Miller
Hepatoprotective effect
Liver fibrosis
Kurumlar
Van Yüzüncü Yıl Üniversitesi
Van Turkey
Metrikler
44
Atıf
7
Yazar
6
Anahtar Kelime