Scopus
🔓 Açık Erişim YÖKSİS Eşleşti
L-carnitine alleviates sciatic nerve crush injury in rats: Functional and electron microscopy assessments
Neural Regeneration Research · Mayıs 2014
YÖKSİS Kayıtları
L carnitine alleviates sciatic nerve crush injury in rats functional and electron microscopy assessments
Neural Regeneration Research · 2014 SCI-Expanded
DOKTOR ÖĞRETİM ÜYESİ MUHAMMED YAYLA →
Makale Bilgileri
DergiNeural Regeneration Research
Yayın TarihiMayıs 2014
Cilt / Sayfa9 · 1020-1024
Scopus ID2-s2.0-84902082383
Erişim🔓 Açık Erişim
Özet
Several studies have demonstrated that L-carnitine exhibits neuroprotective effects on injured sciatic nerve of rats with diabetes mellitus. It is hypothesized that L-carnitine exhibits neuroprotective effects on injured sciatic nerve of rats. Rat sciatic nerve was crush injured by a forceps and exhibited degenerative changes. After intragastric administration of 50 and 100 mg/kg L-carnitine for 30 days, axon area, myelin sheath area, axon diameter, myelin sheath diameter, and numerical density of the myelinated axons of injured sciatic nerve were similar to normal, and the function of injured sciatic nerve also improved significantly. These findings suggest that L-carnitine exhibits neuroprotective effects on sciatic nerve crush injury in rats.
Yazarlar (8)
1
Ummu Avsar
2
Umit Avsar
3
Ali Aydin
4
Muhammed Yayla
ORCID: 0000-0002-0659-3084
5
Berna Ozturkkaragoz
6
Harun Un
ORCID: 0000-0003-1772-282X
7
Murat Saritemur
8
Tolga Mercantepe
Anahtar Kelimeler
Axon
Crush injury
Electron microscopy
L-carnitine
Myelin sheath
Nerve regeneration
Neural regeneration
Neuroprotection
Peripheral nerve injury
Sciatic nerve
Kurumlar
Agri University
Agri Turkey
Atatürk Üniversitesi
Erzurum Turkey
Metrikler
9
Atıf
8
Yazar
10
Anahtar Kelime