Scopus
🔓 Açık Erişim YÖKSİS DOI Eşleşti
SJR Q1
A new update for radiocontrast-induced nephropathy aggravated with glycerol in rats: The protective potential of epigallocatechin-3-gallate
Renal Failure · Ocak 2017
YÖKSİS Kayıtları
A new update for radiocontrast-induced nephropathy aggravated with glycerol in rats: the protective potential of epigallocatechin-3-gallate
Renal Failure · 2017 SCI-Expanded
Dr. Öğr. Üyesi MUHAMMED YAYLA →
YÖKSİS Kayıtları — ISSN Eşleşmesi
Effect of Mirtazapine on Oxidative Stress Created in Rat Kidneys by Ischemia Reperfusion
2012 ISSN: 0886-022X SCI-Expanded
Prof. Dr. NİHAL ÇETİN →
Ultrasound validation of Trendelenburg positioning to increase internal jugular vein cross sectional area in chronic dialysis patients
2015 ISSN: 0886-022X SCI-Expanded
Prof. Dr. İBRAHİM ÖZKAN ÖNAL →
Coenzyme Q10 and its Relation with Oxidant and Antioxidant System Markers in Patients with End Stage Renal Disease
2011 ISSN: 0886-022X SCI-Expanded
Prof. Dr. MUAZ BELVİRANLI →
Ultrasound validation of Trendelenburg positioning to increase internal jugular vein cross sectional area in chronic dialysis patients
2015 ISSN: 0886-022X SCI-Expanded
Prof. Dr. ALAADDİN NAYMAN →
Clinical Outcome Following the Use of Inadequate Solutions for Continuous Veno Venous Hemodiofiltration
2008 ISSN: 0886-022X SCI-Expanded
Prof. Dr. JALE BENGİ ÇELİK →
Effect of Off Pump and On Pump Coronary Artery Bypass Grafting on Renal Function
2005 ISSN: 0886-022X SCI-Expanded 3 atıf
Prof. Dr. JALE BENGİ ÇELİK →
Predictors of Kidney Dimensions Measured by Multi detector Computed Tomography MDCT in 930 Middle Aged and Elderly Patients
2012 ISSN: 0886-022X SCI-Expanded
Prof. Dr. ALAADDİN NAYMAN →
Ultrasound validation of Trendelenburg positioning to increase internal jugular vein cross sectional area in chronic dialysis patients
2015 ISSN: 0886-022X SCI-Expanded
Prof. Dr. JALE BENGİ ÇELİK →
Effect of Off Pump and On Pump Coronary Artery Bypass Grafting on Renal Function
2005 ISSN: 0886-022X SCI-Expanded 1 atıf
Prof. Dr. JALE BENGİ ÇELİK →
Prevalence of Nasal Staphylococcus aureus Carriage in the Patients Undergoing Hemodialysis and Evaluation of Risk Factors and Laboratory Parameters title
2011 ISSN: 0886-022X SCI-Expanded
Prof. Dr. GÜLPERİ ÇELİK →
Regressive course of oxalate deposition in primary hyperoxaluria after kidney transplantation
2010 ISSN: 0886-022X SCI-Expanded
Prof. Dr. GÜLPERİ ÇELİK →
The Relationship Between Neutrophil to Lymphocyte Ratio and Inflammation in End Stage Renal Disease Patients
2011 ISSN: 0886-022X SCI-Expanded
Prof. Dr. FATMA HÜMEYRA YERLİKAYA AYDEMİR →
Ultrasound validation of Trendelenburg positioning to increase internal jugular vein cross sectional area in chronic dialysis patients
2015 ISSN: 0886-022X SCI-Expanded
Prof. Dr. JALE BENGİ ÇELİK →
Effect of Off Pump and On Pump Coronary Artery Bypass Grafting on Renal Function
2005 ISSN: 0886-022X SCI-Expanded
Prof. Dr. JALE BENGİ ÇELİK →
Coenzyme Q 10 and its Relation with Oxidant and Antioxidant SystemMarkers in Patients with End Stage Renal Disease
2011 ISSN: 0886-022X SSCI 3 atıf
Prof. Dr. NİLSEL OKUDAN →
The Effects of Sevoflurane Anesthesia and Cardiopulmonary Bypass on Renal Function in Cyanotic and Acyanotic Children Undergoing Cardiac Surgery
2011 ISSN: 0886-022X SCI
Prof. Dr. BAHAR ÖÇ →
Optimal Angle of Needle Entry for Internal Jugular Vein Catheterization with a Neutral Head Position A CT Study
2013 ISSN: 0886-022X SCI-Expanded
Prof. Dr. MUSTAFA KOPLAY →
A new update for radiocontrast-induced nephropathy aggravated with glycerol in rats: the protective potential of epigallocatechin-3-gallate
2017 ISSN: 0886-022X SCI-Expanded
Dr. Öğr. Üyesi MUHAMMED YAYLA →
The assessment of P-wave dispersion and myocardial repolarization parameters in patients with chronic kidney disease
2018 ISSN: 0886-022X SCI-Expanded
Prof. Dr. LÜTFULLAH ALTINTEPE →
Correlation between Proteinuria Level and Renal Morphology with Special Reference to Electron Microscopy in Kidney Donors
2009 ISSN: 0886-022X SCI-Expanded
Dr. Öğr. Üyesi NEJAT ÜNLÜKAL →
Makale Bilgileri
Dergi
Renal Failure
ISSN0886022X
Yayın TarihiOcak 2017
Cilt / Sayfa39 · 314-322
Scopus ID2-s2.0-85016126121
Erişim🔓 Açık Erişim
Özet
Contrast media (CM) is known to have nephrotoxic adverse effects. Epigallocatechin-3-gallate (EGCG) is the most abundant and active catechin in green tea, and has strong antioxidant and anti-inflammatory properties. This study investigated whether EGCG can reduce contrast-induced nephrotoxicity (CIN), alone or with glycerol (GLY)-induced renal damage, and to understand its mechanisms of protection against toxicity, using models of GLY and CIN in rats. The rats were separated into eight groups (n=6 in each), as follows: Healthy, GLY, CM, GLY+CM, CM+EGCG 50mg/kg (po), GLY+CM+EGCG 50mg/kg (po), CM+EGCG 100mg/kg (po), and GLY+CM+EGCG 100mg/kg (po). Both doses of EGCG protected against CM-induced renal dysfunction, as measured by serum creatinine and blood urea nitrogen (BUN). In addition, EGCG treatment markedly improved CIN-induced oxidative stress, and resulted in a significant down-regulatory effect on tumor necrosis factor (TNF)-α and nuclear factor (NF)-κB mRNA expression. Moreover, histopathological analysis showed that EGCG also attenuated CM-induced kidney damage. Considering the potential clinical use of CM and the numerous health benefits of EGCG, this study showed the protective role of multi-dose EGCG treatment on CIN and GLY-aggravated CIN through different mechanisms.
Yazarlar (8)
1
Saziye Sezin Palabiyik
2
Busra Dincer
ORCID: 0000-0002-3365-7741
3
Elif Cadirci
4
Irfan Cinar
ORCID: 0000-0002-9826-2556
5
Cemal Gundogdu
6
Beyzagul Polat
7
Muhammed Yayla
ORCID: 0000-0002-0659-3084
8
Zekai Halici
Anahtar Kelimeler
Contrast media
EGCG
Nephrotoxicity
Rat
Kurumlar
Atatürk Üniversitesi
Erzurum Turkey
Ataturk University, Faculty of Medicine
Erzurum Turkey
Erzincan Binali Yıldırım Üniversitesi
Erzincan Turkey
Kafkas Üniversitesi
Kars Turkey
Scimago Dergi (ISSN Eşleşmesi)
Renal Failure
Q1
OA
SJR Skoru0,946
H-Index76
YayıncıTaylor and Francis Ltd.
ÜlkeUnited Kingdom
Critical Care and Intensive Care Medicine (Q1)
Medicine (miscellaneous) (Q1)
Nephrology (Q1)
Metrikler
18
Atıf
8
Yazar
4
Anahtar Kelime