Scopus
YÖKSİS DOI Eşleşti
SJR Q1
Does daily fasting shielding kidney on hyperglycemia-related inflammatory cytokine via TNF-α, NLRP3, TGF-β1 and VCAM-1 mRNA expression
International Journal of Biological Macromolecules · Kasım 2021
YÖKSİS Kayıtları
Does daily fasting shielding kidney on hyperglycemia-related inflammatory cytokine via TNF-α, NLRP3, TGF-β1 and VCAM-1 mRNA expression
International Journal of Biological Macromolecules · 2021 SCI
Dr. Öğr. Üyesi MUHAMMED YAYLA →
YÖKSİS Kayıtları — ISSN Eşleşmesi
Immobilization and characterization of hemoglobin on modified sporopollenin surfaces
2012 ISSN: 0141-8130 SCI 2 atıf
Prof. Dr. MUSTAFA ÖZMEN →
Binding of actin to thioglycolic acid modified superparamagnetic nanoparticles for antibody conjugation
2015 ISSN: 01418130 SCI-Expanded
Prof. Dr. ESRA MALTAŞ ÇAĞIL →
Immobilization and characterization of hemoglobin on modified sporopollenin surfaces
2012 ISSN: 01418130 SCI-Expanded 1 atıf
Prof. Dr. ESRA MALTAŞ ÇAĞIL →
Magnetic nanoparticles serum proteins bioconjugates for binding of irinotecan
2015 ISSN: 01418130 SCI-Expanded
Prof. Dr. SALİH ZEKİ BAŞ →
Immobilization of Candida rugosa lipase on sporopollenin from Lycopodium clavatum
2009 ISSN: 0141-8130 SCI-Expanded
Prof. Dr. ELİF ÖZYILMAZ →
Magnetic nanoparticles serum proteins bioconjugates for binding of irinotecan
2015 ISSN: 01418130 SCI-Expanded
Prof. Dr. ESRA MALTAŞ ÇAĞIL →
Synthesis and characterization of novel nano chitosan Schiff base and use of lead II sensor
2012 ISSN: 01418130 SCI-Expanded 7 atıf
Prof. Dr. SEMAHAT KÜÇÜKKOLBAŞI →
Chitosan sporopollenin microcapsules Preparation characterisation and application in heavy metal removal
2015 ISSN: 01418130 SCI-Expanded
Prof. Dr. GÜLŞİN ARSLAN →
Immobilization and characterization of hemoglobin on modified sporopollenin surfaces
2012 ISSN: 01418130 SCI-Expanded 1 atıf
Prof. Dr. İLKAY HİLAL GÜBBÜK →
Magnetic nanoparticles serum proteins bioconjugates for binding of irinotecan
2015 ISSN: 01418130 SCI-Expanded 2 atıf
Prof. Dr. MUSTAFA ÖZMEN →
Characteristics of corneal lens chitin in dragonfly compound eyes
2016 ISSN: 01418130 SCI
Prof. Dr. GÜLŞİN ARSLAN →
Evaluation of antibacterial properties on polysulfone composite membranes using synthesized biogenic silver nanoparticles with Ulva compressa (L.) Kütz. and Cladophora glomerata (L.) Kütz. extracts
2018 ISSN: 01418130 SSCI
Prof. Dr. MUSTAFA ERSÖZ →
Supplementing capsaicin with chitosan-based films enhanced the anti-quorum sensing, antimicrobial, antioxidant, transparency, elasticity and hydrophobicity
2018 ISSN: 0141-8130 SCI
Prof. Dr. İDRİS SARGIN →
Characteristics of corneal lens chitin in dragonfly compound eyes
2016 ISSN: 01418130 SCI
Prof. Dr. İDRİS SARGIN →
Chitin extraction and characterization from Daphnia magna resting eggs
2013 ISSN: 0141-8130 SCI
Prof. Dr. İDRİS SARGIN →
Chitosan nanofiber production from Drosophila by electrospinning
2016 ISSN: 01418130 SCI
Prof. Dr. İDRİS SARGIN →
Chitosan/sporopollenin microcapsules: Preparation, characterisation and application in heavy metal removal
2015 ISSN: 01418130 SCI
Prof. Dr. İDRİS SARGIN →
Controlled release and anti-proliferative effect of imatinib mesylate loaded sporopollenin microcapsules extracted from pollens of Betula pendula
2017 ISSN: 01418130 SCI
Prof. Dr. İDRİS SARGIN →
Detailed adsorption mechanism of plasmid DNA by newly isolated cellulose from waste flower spikes of Thypa latifolia using quantum chemical calculations
2017 ISSN: 01418130 SCI
Prof. Dr. İDRİS SARGIN →
Effect of different animal fat and plant oil additives on physicochemical, mechanical, antimicrobial and antioxidant properties of chitosan films
2018 ISSN: 0141-8130 SCI
Prof. Dr. İDRİS SARGIN →
Makale Bilgileri
ISSN01418130
Yayın TarihiKasım 2021
Cilt / Sayfa190 · 911-918
Scopus ID2-s2.0-85114951808
Özet
This study aimed to investigate the effects of blood glucose control and the kidneys' functions, depending on fasting, in the streptozotocin-induced diabetes model in rats via TNF-α, NLRP-3, TGF-β1 and VCAM-1 mRNA expression in the present study. 32 Wistar albino rats were allocated randomly into four main groups; H (Healthy, n = 6), HF (Healthy fasting, n = 6), D (Diabetes, n = 10), DF (Diabetes and fasting, n = 10). Blood glucose and HbA1c levels significantly increased in the D group compared to the healthy ones (p < 0.05). However, the fasting period significantly improved blood glucose and HbA1c levels 14 days after STZ induced diabetes in rats compared to the D group. Similar findings we obtained for serum (BUN-creatinine) and urine samples (creatinine and urea levels). STZ induced high glucose levels significantly up-regulated TNF-α, NLRP-3, TGF-β1 and VCAM-1 mRNA expression and fasting significantly decreased these parameters when compared to diabetic rats. Histopathological staining also demonstrated the protective effects of fasting on diabetic kidney tissue. In conclusion, intermittent fasting regulated blood glucose level as well as decreasing harmful effects of diabetes on kidney tissue. The fasting period significantly decreased the hyperglycemia-related inflammatory cytokine damage on kidneys and also reduced apoptosis in favor of living organisms.
Yazarlar (10)
1
Arzu Bilen
2
Ilknur Calik
3
Muhammed Yayla
ORCID: 0000-0002-0659-3084
4
Busra Dincer
ORCID: 0000-0002-3365-7741
5
Taha Tavaci
6
Irfan Cinar
ORCID: 0000-0002-9826-2556
7
Habip Bilen
8
Elif Cadirci
9
Zekai Halici
10
Filiz Mercantepe
Anahtar Kelimeler
Diabetes
Fasting
Kidney
Rat
Kurumlar
Atatürk Üniversitesi
Erzurum Turkey
Ataturk University, Faculty of Medicine
Erzurum Turkey
Erzincan Binali Yıldırım Üniversitesi
Erzincan Turkey
Firat Üniversitesi Tip Fakültesi
Elazig Turkey
Kafkas Üniversitesi
Kars Turkey
Kastamonu University
Kastamonu Turkey
Scimago Dergi (ISSN Eşleşmesi)
International Journal of Biological Macromolecules
Q1
SJR Skoru1,287
H-Index247
YayıncıElsevier B.V.
ÜlkeNetherlands
Biochemistry (Q1)
Biomaterials (Q1)
Food Science (Q1)
Structural Biology (Q1)
Molecular Biology (Q2)
Metrikler
19
Atıf
10
Yazar
4
Anahtar Kelime