Scopus
YÖKSİS Eşleşti
Aquaporins: Potential Targets in Inflammatory Diseases
Eurasian Journal of Medicine · Aralık 2023
YÖKSİS Kayıtları
Aquaporins: Potential Targets in Inflammatory Diseases
The Eurasian Journal of Medicine · 2024 scopus
DOKTOR ÖĞRETİM ÜYESİ MUHAMMED YAYLA →
Makale Bilgileri
DergiEurasian Journal of Medicine
Yayın TarihiAralık 2023
Cilt / Sayfa55 · S106-S113
Scopus ID2-s2.0-85186559920
Özet
Inflammation involves a long chain of molecular reactions and cellular activity designed to repair tissue dam-aged by various causes. The inflammatory process and its complex mechanisms have recently become a focus of interest for many researchers. After the onset of inflammation, various adverse conditions that initiate the inflammatory response need to be addressed; however, failure to limit the inflammatory reaction may result in the damage or destruction of host cells. Therefore, inflammatory reactions play a role in many different diseases. Aquaporins (AQPs), commonly referred to as water channels, are protein channels responsible for forming pores in the membranes of biological cells. Their main function is to aid in the movement of water between cells. Aquaporins not only regulate transepithelial fluid transport across membranes but also play a role in regulating essential events crucial for the inflammatory response. Aquaporins have been shown in many studies to have important roles in inflammatory diseases. This clearly indicates that AQPs may be potential targets for inflammatory diseases. This review summarizes the research to date on the structure and function of AQPs and provides an update on the relationship between AQPs and various human inflammatory diseases.
Yazarlar (3)
1
Ayse Bozkurt
2
Hamza Halici
3
Muhammed Yayla
ORCID: 0000-0002-0659-3084
Anahtar Kelimeler
Aquaporin
disease
inflammation
membrane
water
Kurumlar
Atatürk Üniversitesi
Erzurum Turkey
Kafkas Üniversitesi
Kars Turkey
Van Yüzüncü Yıl Üniversitesi
Van Turkey