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Biological activities and DNA interactions of Amanita ovoidea

Pharmaceutical Biology · Ocak 2015

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YÖKSİS Kayıtları
Biological activities and DNA interactions of Amanita ovoidea
PHARMACEUTICAL BIOLOGY · 2015 SCI-Expanded
Prof. Dr. HASAN HÜSEYİN DOĞAN →
Biological activities and DNA interactions of Amanita ovoidea
Pharmaceutical Biology · 2015 SCI-Expanded
Prof. Dr. EMİNE ARSLAN →
YÖKSİS ISSN Eşleşmesi

Bu dergide (ISSN eşleşmesi) kurumun 11 kaydı bulundu.

YÖKSİS Kayıtları — ISSN Eşleşmesi
Implications from a pharmacogenomic analysis Nerium oleander leaf distillate supplemented diet regulates cholesterol metabolism in rats
2014 ISSN: 1388-0209 SCI-Expanded
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Epilobium hirsutum alters xenobiotic metabolizing CYP1A1 CYP2E1 NQO1 and GPx activities mRNA and protein levels in rats
2013 ISSN: 1388-0209 SCI-Expanded 3 atıf
Prof. Dr. SERDAR KARAKURT →
Implications from a pharmacogenomic analysis Nerium oleander leaf distillate supplemented diet regulates cholesterol metabolism in rats
2014 ISSN: 1388-0209 SCI-Expanded
Prof. Dr. AHMET LEVENT BAŞ →
Biological activities and DNA interactions of Amanita ovoidea
2015 ISSN: 1388-0209 SCI-Expanded
Prof. Dr. HASAN HÜSEYİN DOĞAN →
Implications from a pharmacogenomic analysis Nerium oleander leaf distillate supplemented diet regulates cholesterol metabolism in rats
2014 ISSN: 1388-0209 SCI-Expanded
Prof. Dr. AHMET LEVENT BAŞ →
Biological activities and DNA interactions of Amanita ovoidea
2015 ISSN: 1388-0209 SCI-Expanded
Prof. Dr. EMİNE ARSLAN →
Biological activity and fatty acid composition of Caesar s mushroom
2013 ISSN: 1388-0209 SCI-Expanded 2 atıf
Prof. Dr. HASAN HÜSEYİN DOĞAN →
Antimicrobial activities of some mushrooms in Turkey
2013 ISSN: 1388-0209 SCI-Expanded 1 atıf
Prof. Dr. HASAN HÜSEYİN DOĞAN →
Implications from a pharmacogenomic analysis: iNerium oleander/i leaf distillate supplemented diet regulates cholesterol metabolism in rats/title
2014 ISSN: 1388-0209 SCI-Expanded
Prof. Dr. AHMET LEVENT BAŞ →
Antimicrobial Activities of Some Plants from the Eastern Anatolia Region of Turkey
2005 ISSN: 1388-0209 SCI
Prof. Dr. MEHMET TUZCU →
Isoquinoline alkaloids isolated from Glaucium corniculatum var. corniculatum and Glaucium grandiflorum subsp. Refractum var. torquatum with bioactivity studies
2023 ISSN: 1388-0209 SCI-Expanded Q1
Prof. Dr. OSMAN TUGAY →

Makale Bilgileri

Dergi Pharmaceutical Biology
ISSN13880209
Yayın TarihiOcak 2015
Cilt / Sayfa53 · 1386-1390
DOI10.3109/13880209.2014.982303
Scopus ID2-s2.0-84943147244
Erişim🔓 Açık Erişim
Özet Context: Amanita ovoidea (Bull.) Link (Amanitaceae) is a well-known species due to its pleasant aroma and flavor since ancient times in the worldwide. This species is also known in Turkey and people consume it extensively. Objective: To evaluate medicinal importance of A. ovoidea for human health, to explain the effect of mushroom extracts on bacterial DNA, and to find preventive role on bacterial disease. Materials and methods: Chloroform, acetone, and methanol extracts of A. ovoidea were tested for the antimicrobial activities against four Gram-positive bacteria, five Gram-negative bacteria, and yeast using a micro-dilution method. In addition, DNA binding, DNA cleavage activity, and restriction enzyme digestion of the methanol extract of A. ovoidea were examined at different concentrations (40.000-78.125μg/mL). Results: The highest minimum inhibitory concentration (MIC) value observed against the test micro-organisms was with the chloroform extract (MIC 19.5μg/mL concentration) against Candida albicans. Other highest antimicrobial effects observed against the test micro-organisms were with the methanol extracts against Bacillus subtilis, Staphylococcus aureus, Listeria monocytogenes, Streptococcus pyogenes, Candida albicans, Klebsiella pneumoniae, Proteus vulgaris, and Salmonella enteritidis (MICs, 78μg/mL concentrations). All concentrations reduced the mobility of plasmid DNA. BamHI and HindIII targeted specially to supercoils and cut them. Amanita ovoidea extract prevented cutting with HindIII by binding especially to the AA region in open circular DNA. Discussion and conclusion: Present results demonstrated that A. ovoidea has excellent antimicrobial and antifungal activities by its DNA interaction activity on pBR322.

Yazarlar (2)

1
Hasan Hüseyin Doʇan
2
Emine Arslan

Anahtar Kelimeler

Antimicrobial activity DNA binding DNA cleavage micro-dilution

Kurumlar

Selçuk Üniversitesi
Selçuklu Turkey
Scimago Dergi (ISSN Eşleşmesi)
Pharmaceutical Biology
Q1 OA
SJR Skoru1,121
H-Index103
YayıncıTaylor and Francis Ltd.
ÜlkeUnited Kingdom
Complementary and Alternative Medicine (Q1)
Drug Discovery (Q1)
Medicine (miscellaneous) (Q1)
Pharmaceutical Science (Q1)
Pharmacology (Q1)
Molecular Medicine (Q2)
Dergi sayfasına git

Metrikler

3
Atıf
2
Yazar
4
Anahtar Kelime

Sistemimizdeki Yazarlar

EA
EMİNE ARSLAN
Prof. Dr.

Hızlı Erişim

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