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Nonfunctioning Pituitary Adenomas Are Really Clinically Nonfunctioning? Clinical and Endocrinological Symptoms and Outcomes with Endoscopic Endonasal Treatment

World Neurosurgery · Ocak 2016

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YÖKSİS Kayıtları
Nonfunctioning Pituitary Adenomas Are Really Clinically Nonfunctioning? Clinical and Endocrinological Symptoms and Outcomes with Endoscopic Endonasal Treatment
WORLD NEUROSURGERY · 2016 SCI-Expanded
Doç. Dr. DERYA KARAOĞLU GÜNDOĞDU →
Nonfunctioning Pituitary Adenomas Are Really Clinically Nonfunctioning Clinical and Endocrinological Symptoms and Outcomes with Endoscopic Endonasal Treatment
World Neurosurgery · 2016 SCI-Expanded
Doç. Dr. MERT ŞAHİNOĞLU →
YÖKSİS ISSN Eşleşmesi

Bu dergide (ISSN eşleşmesi) kurumun 13 kaydı bulundu.

YÖKSİS Kayıtları — ISSN Eşleşmesi
Nonfunctioning Pituitary Adenomas Are Really Clinically Nonfunctioning Clinical and Endocrinological Symptoms and Outcomes with Endoscopic Endonasal Treatment
2016 ISSN: 18788750 SCI-Expanded
Doç. Dr. MERT ŞAHİNOĞLU →
Treatment of Unstable Thoracolumbar Fractures: Does Fracture-Level Fixation Accelerate the Bone Healing?
2017 ISSN: 1878-8750 SCI-Expanded Q2
Doç. Dr. HASAN ÖNNER →
Iliac Artery Injury During Lumbar Disc Hernia Surgery
2019 ISSN: 1878-8750 SCI-Expanded
Doç. Dr. MERT ŞAHİNOĞLU →
Small Cell Lung Carcinoma Metastasis to Atypical Meningioma: Importance of Perfusion Magnetic Resonance Imaging Graphics in Differential Diagnosis
2019 ISSN: 1878-8750 SCI-Expanded
Prof. Dr. ENDER KÖKTEKİR →
Iliac Artery Injury During Lumbar Disc Hernia Surgery
2019 ISSN: 1878-8750 SCI-Expanded Q4
Prof. Dr. OĞUZHAN ARUN →
Small Cell Lung Carcinoma Metastasis to Atypical Meningioma: Importance of Perfusion Magnetic Resonance Imaging Graphics in Differential Diagnosis
2019 ISSN: 1878-8750 SCI-Expanded
Prof. Dr. MUSTAFA KOPLAY →
Iliac Artery Injury During Lumbar Disc Hernia Surgery
2019 ISSN: 1878-8750 SCI-Expanded
Doç. Dr. AKIN ÇALIŞIR →
Iliac Artery Injury During Lumbar Disc Hernia Surgery
2019 ISSN: 1878-8750 SCI-Expanded
Doç. Dr. ATİLLA ORHAN →
Neuroprotective Effects of Milrinone on Experimental Acute Spinal Cord Injury: Rat Model
2021 ISSN: 1878-8750 SCI-Expanded Q3
Prof. Dr. FATMA HÜMEYRA YERLİKAYA AYDEMİR →
Neuroprotective Effects of Milrinone on Experimental Acute Spinal Cord Injury: Rat Model
2021 ISSN: 1878-8750 SCI-Expanded Q3
Prof. Dr. FATMA HÜMEYRA YERLİKAYA AYDEMİR →
Nonfunctioning Pituitary Adenomas Are Really Clinically Nonfunctioning? Clinical and Endocrinological Symptoms and Outcomes with Endoscopic Endonasal Treatment
2016 ISSN: 1878-8750 SCI-Expanded Q2
Doç. Dr. DERYA KARAOĞLU GÜNDOĞDU →
Intradural Spinal Arachnoid Cysts in Children: A Collective Experience of 2 Centers
2023 ISSN: 1878-8750 SCI-Expanded Q3
Doç. Dr. BURAK GEZER →
Iliac Artery Injury During Lumbar Disc Hernia Surgery
2019 ISSN: 1878-8750 SCI-Expanded Q3
Doç. Dr. ATİLLA ORHAN →

Makale Bilgileri

Dergi World Neurosurgery
ISSN18788750
Yayın TarihiOcak 2016
Cilt / Sayfa85 · 185-192
DOI10.1016/j.wneu.2015.08.073
Scopus ID2-s2.0-84948844935
Özet Background: Nonfunctioning pituitary adenomas are the most common pituitary adenomas in adults and cause significant morbidity unless adequately treated. Methods: This study retrospectively assessed the medical records of 160 patients operated via pure endonasal endoscopy. The presenting symptoms, results of neurologic and visual examinations, levels of pituitary hormones, results of radiologic examinations, size of the adenoma, rates of resection, results of postoperative visual examination, and pituitary hormone levels at follow-up were recorded to establish the appropriate approach, operative criteria, and outcomes of patients with nonfunctioning pituitary adenoma. Results: Headache was the presenting symptom in 87.5% of the patients. Thirty-three percent had visual loss, and visual examinations on the whole study population revealed a visual field defect in 47.5% of the patients. Only 16.25% of the patients presented with endocrinological symptoms; 52.5% had abnormal anterior pituitary hormone levels. Regarding adenoma size, 56 patients had macroadenoma (35%), 84 (52.5%) had mesoadenoma, and 20 patients had giant adenoma. Gross total resection was achieved in 90% of the patients; subtotal resection was achieved in the remainder. The rate of total resection was lower for giant adenomas and recurrences. Visual symptoms and anterior pituitary hormone levels improved in 27 and 42 patients, respectively, after the operation. Conclusions: Nonfunctioning pituitary adenomas present frequently as mesoademonas and giant adenomas. Patients with these tumors may have subclinical visual or hormonal deficits at the time of diagnosis. Early and effective surgical treatment is essential for rapid recovery of visual and/or hormonal deficits, particularly in symptomatic cases.

Yazarlar (8)

1
A. E. Yildirim
2
Mert Sahinoglu
ORCID: 0000-0003-0633-8304
3
Ibrahim Ekici
4
Emin Cagil
5
Derya Karaoglu
6
H. Celik
7
Osman Arikan Nacar
8
A. D. Belen

Anahtar Kelimeler

Endonasal Endoscopy Nonfunctioning Pituitary adenoma

Kurumlar

Ankara Numune Education and Research Hospital
Ankara Turkey
Scimago Dergi (ISSN Eşleşmesi)
World Neurosurgery
Q2
SJR Skoru0,709
H-Index123
YayıncıElsevier Inc.
ÜlkeUnited States
Neurology (clinical) (Q2)
Surgery (Q2)
Dergi sayfasına git

Metrikler

24
Atıf
8
Yazar
4
Anahtar Kelime

Sistemimizdeki Yazarlar

MŞ
MERT ŞAHİNOĞLU
Doç. Dr.

Hızlı Erişim

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