Scopus
🔓 Açık Erişim YÖKSİS DOI Eşleşti
SJR Q2
Nutritional and pharmacological potentials of the medicinal mushroom Ganoderma adspersum (Schulz.) Donk
South African Journal of Botany · Mart 2024
YÖKSİS Kayıtları
NutritionalandpharmacologicalpotentialsofthemedicinalmushroomGanodermaadspersum(Schulz.)Donk
South African Journal of Botany · 2024 SCI-Expanded
Prof. Dr. HASAN HÜSEYİN DOĞAN →
YÖKSİS Kayıtları — ISSN Eşleşmesi
Novel perspectives on two Digitalis species: Phenolic profile, bioactivity, enzyme inhibition, and toxicological evaluation
2017 ISSN: 02546299 SCI-Expanded
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2019 ISSN: 0254-6299 SCI-Expanded
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Gundelia rosea seed: Evaluation of biopharmaceutical potential and bioactive composition
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Gundelia rosea seed: Evaluation of biopharmaceutical potential and bioactive composition
2019 ISSN: 0254-6299 SCI-Expanded Q2
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Enzyme inhibitory and antioxidant properties of six mushroom species from the Agaricaceae family
2019 ISSN: 02546299 SCI-Expanded
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In vitro tyrosinase inhibitory and antioxidant potential of Consolida orientalis, Onosma isauricum and Spartium junceum from Turkey
2019 ISSN: 0254-6299 SCI
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Chemical profile, antioxidant properties and enzyme inhibitory effects of the root extracts of selected Potentilla species
2019 ISSN: 0254-6299 SCI
Prof. Dr. GÖKHAN ZENGİN →
Chemical profile, antioxidant properties and enzyme inhibitory effects of the root extracts of selected Potentilla species
2019 ISSN: 0254-6299 SCI-Expanded
Prof. Dr. GÖKHAN ZENGİN →
Enzyme inhibitory and antioxidant properties of six mushroom species from the Agaricaceae family
2019 ISSN: 0254-6299 SCI-Expanded
Prof. Dr. GÖKHAN ZENGİN →
Biopharmaceutical potential, chemical profile and in silico study of the seagrass– Syringodium isoetifolium (Asch.) Dandy
2019 ISSN: 0254-6299 SCI-Expanded
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Gundelia rosea seed: Evaluation of biopharmaceutical potential and bioactive composition
2019 ISSN: 0254-6299 SCI-Expanded
Prof. Dr. GÖKHAN ZENGİN →
In vitro tyrosinase inhibitory and antioxidant potential of Consolida orientalis, Onosma isauricum and Spartium junceum from Turkey
2019 ISSN: 0254-6299 SCI-Expanded
Prof. Dr. GÖKHAN ZENGİN →
Chemical profile, antioxidant properties and enzyme inhibitory effects of the root extracts of selected Potentilla species
2019 ISSN: 0254-6299 SCI-Expanded
Prof. Dr. GÖKHAN ZENGİN →
Asphodeline cilicica Tuzlaci: From the plant to its most active part extract and its broad bioactive properties
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In vitro plant regeneration, and jasmonic acid induced bioactive chemical accumulations in two Hypericum species from Turkey.
2020 ISSN: 0254-6299 SCI-Expanded
Prof. Dr. ERTAN SAİT KURTAR →
Makale Bilgileri
ISSN02546299
Yayın TarihiMart 2024
Cilt / Sayfa166 · 360-374
Scopus ID2-s2.0-85183515108
Erişim🔓 Açık Erişim
Özet
In this study, the nuraceutical and the pharmacological properties of the crude extract of a wild mushroom, Ganoderma adspersum (Schulz.) Donk collected from Tunisia, were investigated. The antioxidant, antibacterial, antiviral (HSV-1) activities as well as antiproliferative potential against humain breast cancer (MCF-7) cells in vitro were studied. The fruiting body of Ganoderma revealed high protein and carbohydrates contents as well as a rich minerals composition and a low fat content. The crude extract exhibited a strong scavenging activity against ABTS+ radicals (IC50 = 9.75 μg/mL) and a powerful antibacterial activity against all tested Gram-positive bacteria. In this respect, the tested extract displayed an acceptable cytotoxicity limit towards normal Vero cells with a maximum non-toxic concentration value (MNTC) of 1.53 mg/mL as well as a proliferation ability which reached 108.19 % and 113.83 mg/mL at MNTC and 0.781 mg/mL concentrations, respectively. In addition, at concentration of 1.5 mg/mL, the extract exhibited an antiviral capacity against the Herpes Simplex Virus (HSV-1) with a potent selective index of 40 and a high percentage of protection of 84.7 % as well as a significant inhibition of MCF-7 cancer cells (16. 23 % ± 0.08). Our results corroborate the dietetic profile of G. adspersum as well as the medicinal potential of its crude extract, which could promote beneficial effects on human health. This is the first report on the antiviral HSV-1 and anticancer properties of a hydroalcholic extract of G. adspersum which highlights its potential as a natural source of bioactive components that can be isolated and tested in vivo.
Yazarlar (13)
1
Sana Hamrouni Zahmoul
2
Rim Ladhar Chaabouni
3
Ameny Srih
4
Hasan Huseyin Dogan
5
Elif Varıcıoğlu
ORCID: 0000-0003-2221-8353
6
Imed Sbissi
ORCID: 0000-0002-5703-5760
7
Ursula Kües
ORCID: 0000-0001-9180-4079
8
Lamjed Toumi
9
Ali Tlili
10
Gregorio Peron
ORCID: 0000-0002-6007-6184
11
Nacim Louhichi
12
Mohamed Trigui
13
Karama Zouari Bouassida
Anahtar Kelimeler
Antibacterial
Antioxidant
Anti-proliferative
Antiviral
Ganoderma adspersum
Hydro-alcoholic extract
Mushroom
Kurumlar
Centre de Biotechnologie de Sfax
Sfax Tunisia
Faculté des Sciences de Sfax
Sfax Tunisia
Georg-August-Universität Göttingen
Gottingen Germany
Institut Sylvo-Pastoral de Tabarka
Tabarka Tunisia
Selçuk Üniversitesi
Selçuklu Turkey
Università degli Studi di Brescia
Brescia Italy
Université de Gabès
Gabes Tunisia
University of Sfax
Sfax Tunisia
Scimago Dergi (ISSN Eşleşmesi)
South African Journal of Botany
Q2
SJR Skoru0,558
H-Index92
YayıncıElsevier B.V.
ÜlkeNetherlands
Plant Science (Q2)
Metrikler
6
Atıf
13
Yazar
7
Anahtar Kelime