Scopus
🔓 Açık Erişim YÖKSİS Eşleşti
The role of prohepcidin and hepcidin in anemia associated with behçet's disease
UHOD - Uluslararasi Hematoloji-Onkoloji Dergisi · Temmuz 2012
YÖKSİS Kayıtları
The Role of Prohepcidin and Hepcidin in Anemia Associated with Behçet s Disease
UHOD · 2012 SCI-Expanded
PROFESÖR ABDULLAH SİVRİKAYA →
The Role of Prohepcidin and Hepcidin in Anemia Associated with Behcet\u2019s Disease
International Journal of Hematology and Oncology · 2012 SCI-Expanded
PROFESÖR GÜLPERİ ÇELİK →
Makale Bilgileri
DergiUHOD - Uluslararasi Hematoloji-Onkoloji Dergisi
Yayın TarihiTemmuz 2012
Cilt / Sayfa22 · 94-98
Scopus ID2-s2.0-84863863192
Erişim🔓 Açık Erişim
Özet
The aim of the study is to investigate the role of circulating prohepcidin and hepcidin, which are homeostatic regulators of iron metabolism and mediators of inflammation, in anemia associated with Behçet's disease (BD) and the differential diagnosis of healthy controls. Twenty patients with BD and twenty healthy controls were included in this prospective study. Laboratory tests including complete blood count, serum prohepcidin, hepcidin, iron, total iron binding capacity (TIBC), transferrin, ferritin, erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP) were determined. Serum prohepcidin and hepcidin levels in patients with BD were significantly higher than healthy group. In the group with BD positive correlation was determined between the values of serum prohepcidin, hepcidin, hemoglobin, total binding capacity and ferritine. Serum prohepcidin and hepcidin levels are closely associated with disease activity in patients and might play a role in the pathobiology of chronic disease anemia associated with patients with BD.
Yazarlar (4)
1
Mehmet Dagli
2
Sema Yılmaz
ORCID: 0000-0003-4277-3880
3
Abdullah Sivrikaya
4
Gülperi Çelik
Anahtar Kelimeler
Anemia
Behçet's disease
Hepcidin
Prohepcidin
Kurumlar
Selçuk Üniversitesi
Selçuklu Turkey
Metrikler
2
Atıf
4
Yazar
4
Anahtar Kelime