Scopus
🔓 Açık Erişim YÖKSİS DOI Eşleşti
SJR Q4
Serum prohepcidin and hepcidin levels in patients with rheumatoid arthritis: A prospective study
Turkiye Klinikleri Journal of Medical Sciences · Ocak 2013
YÖKSİS Kayıtları
Serum Prohepcidin and Hepcidin Levels in Patients with Rheumatoid Arthritis A Prospective Study
Turkiye Klinikleri Journal of Medical Sciences · 2013 Scopus
Prof. Dr. ABDULLAH SİVRİKAYA →
YÖKSİS Kayıtları — ISSN Eşleşmesi
Evaluation of Retinal Nerve Fiber Layer Thickness with Optical Coherence Tomography in Type 1 Diabetes Mellitus Patients
2011 ISSN: 13000292 SCI-Expanded 2 atıf
Prof. Dr. ŞABAN GÖNÜL →
Medical Treatment of Traumatic Pupillary Capture by Simple Pupil Dilation with Subconjunctival Adrenaline Case Report
2013 ISSN: 1300-0292 Scopus, Index Copernicus, EMBASE/Excerpta Medica
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Serum Prohepcidin and Hepcidin Levels in Patients with Rheumatoid Arthritis A Prospective Study
2013 ISSN: 1300-0292 Scopus
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Revisional Surgery in Bariatric Surgery Initial Experience
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Esophageal Adenocarcinoma Presenting with Skin Metastase Case Report
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Akut Batının Nadir Bir Sebebi İleum İçine Mesh Migrasyonu
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Prof. Dr. FAHRETTİN ACAR →
The Effect of Corset on Walking Time in Lumbar Spinal Stenosis
2009 ISSN: 1300-0292 SCI-Expanded
Prof. Dr. FUNDA LEVENDOĞLU →
A Different Treatment Modality for a Caecal Intramural Duplication Cyst in an Infant Case Report
2013 ISSN: 1300-0292 SCI-Expanded
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Evaluation of Smoking Among Pregnant Women in a Central Anatolian City of Turkey Comparison with Other Countries
2011 ISSN: 13000292 SCI
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A Case Control Study Evaluating Depression and Quality of Life in High Risk Pregnant Women
2010 ISSN: 13000292 SCI
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Examining preeclampsia and eclampsia with two cases in family medicine Medical education
2008 ISSN: 1300-0292 SCI
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Metallobeta Lactamase Enzymes and Antibiotic Susceptibilities in Strains of Pseudomonas Aeruginosa Isolated from Intensive Care Units in Turkey
2012 ISSN: 13000292 SCI-Expanded
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Detection of PER 1 Type Extended Spectrum Beta Lactamase in the Acinetobacter baumannii Species Isolated from Blood Cultures and Investigation of Clonal Relationship
2013 ISSN: 1300-0292 SCI-Expanded
Prof. Dr. UĞUR ARSLAN →
Effects of Mitomycin on Microvascular Anastomosis
2010 ISSN: 13000292 SCI-Expanded
Prof. Dr. HASAN HÜSEYİN DÖNMEZ →
Surgical Outcomes of Ex PRESS Mini Glaucoma Shunt Implantation
2014 ISSN: 1300-0292 türk tıp dizini
Prof. Dr. BANU BOZKURT →
A comparison of virtual colonoscopy with fiberoptic colonoscopy by using 16 detector row computed tomography
2007 ISSN: 1300-0292 SCI-Expanded
Prof. Dr. MUSTAFA KOPLAY →
Treatment of Staple Line Leaks After Laparoscopic Sleeve Gastrectomy With Self Expandable Metalic Stents
2016 ISSN: 1300-0292 EBSCO
Prof. Dr. İLHAN ECE →
Laparoskopik Sleeve Gastrektomi Sonrası Stapler Hattı Kaçaklarının Genişleyebilen Metalik Stentler ile Tedavisi
2016 ISSN: 1300-0292 TR DİZİN
Prof. Dr. HÜSEYİN YILMAZ →
Makale Bilgileri
ISSN13000292
Yayın TarihiOcak 2013
Cilt / Sayfa33 · 946-951
Scopus ID2-s2.0-84884695723
Erişim🔓 Açık Erişim
Özet
Objective: Anemia of chronic disease is a common feature of active rheumatoid arthritis. Hepcidin is an acute-phase protein with specific iron regulatory properties, which along with the anemia seen with increased hepcidin expression, have led many to consider it the major mediator of anemia of chronic disease. The aim of this study was to evaluate the serum levels of hepcidin and its prohormone, prohepcidin, in patients with rheumatoid arthritis (RA) in comparison with healthy controls. Material and Methods: Fifty patients with RA and twenty healthy adults were prospectively enrolled. Complete blood count, erythrocyte sedimentation rate, serum hepcidin, prohepcidin, iron, total iron binding capacity, ferritin, transferrin and C-reactive protein levels were measured. Results: Serum prohepcidin and hepcidin levels were significantly higher in patients with RA compared to healthy controls (p=0.010). In patients with RA, a positive correlation was determined between the serum hepcidin and prohepcidin levels (r=0.725, p<0.001). Conclusion: Our findings suggest that hepcidin and prohepcidin are strongly associated with disease activity in RA patients and might play a significant role in the pathobiology of anemia of chronic disease associated with RA. Future studies to determine serum levels of hepcidin at different time points during the clinical course of RA patients will be needed to confirm our results. © 2013 by Türkiye Klinikleri.
Yazarlar (3)
1
Mehmet Dagli
2
Abdullah Sivrikaya
3
Sema Yılmaz
ORCID: 0000-0003-4277-3880
Anahtar Kelimeler
Arthritis
Hepcidin
Prohepcidin
Rheumatoid
Kurumlar
Departments of Rheumatology
Konya Turkey
Selçuk Üniversitesi
Selçuklu Turkey
Scimago Dergi (ISSN Eşleşmesi)
Turkiye Klinikleri Journal of Medical Sciences
Q4
SJR Skoru0,117
H-Index18
YayıncıTurkiye Klinikleri
ÜlkeTurkey
Medicine (miscellaneous) (Q4)
Metrikler
3
Atıf
3
Yazar
4
Anahtar Kelime