Scopus
YÖKSİS Eşleşti
The relationship between erythrocyte zinc levels and isotretinoin use in acne vulgaris patients
Cutaneous and Ocular Toxicology · Ekim 2015
YÖKSİS Kayıtları
The relationship between erythrocyte zinc levels and isotretinoin use in acne vulgaris patients
Cutaneous and Ocular Toxicology · 2015 SCI-Expanded
PROFESÖR ALİ ÜNLÜ →
The relationship between erythrocyte zinc levels and isotretinoin use in acne vulgaris patients
Cutaneous and Ocular Toxicology · 2015 SCI-Expanded
PROFESÖR ALİ ÜNLÜ →
The relationship between erythrocyte zinc levels and isotretinoin use in acne vulgaris patients
Cutaneous and Ocular Toxicology · 2014 SCI-Expanded
PROFESÖR ALİ ÜNLÜ →
The relationship between erythrocyte zinc levels and isotretinoin use in acne vulgaris patients
Cutaneous and Ocular Toxicology · 2014 SCI-Expanded
PROFESÖR ABDULLAH SİVRİKAYA →
Makale Bilgileri
DergiCutaneous and Ocular Toxicology
Yayın TarihiEkim 2015
Cilt / Sayfa34 · 303-306
Scopus ID2-s2.0-84946093597
Özet
Background: Prior studies have demonstrated lower serum zinc levels in acne vulgaris (AV) patients compared with controls. However, no study has investigated the relationship between AV and erythrocyte zinc levels, which is a superior indicator of body zinc levels. Additionally, the potential influence of isotretinoin use on body zinc status remains to be evaluated. In this study, we aimed to determine erythrocyte zinc levels and their relationship with isotretinoin use in AV patients.Methods: The enrolled study participants included 106 (68% female) isotretinoin-treated AV patients, 89 (65% female) untreated AV patients and 100 (59% female) healthy volunteers between 18 and 30 years of age. The acne severity of the AV patients who did not receive treatment was assessed using the classification system of the International Consensus Conference on Acne. Erythrocyte zinc levels were analysed by atomic absorption spectroscopy.Results: No significant differences were observed among the three groups with respect to erythrocyte zinc levels. In addition, erythrocyte zinc levels did not vary according to the severity of AV, nor according to the duration of isotretinoin use.Conclusion: This study suggests that no relationships exist among zinc status, AV and isotretinoin use. However, given the relationship between Vitamin A and zinc, and the fact that previous studies have indicated low serum zinc levels in AV patients, prospective studies are required to corroborate our data.
Yazarlar (4)
1
Özlem Bilgiç
2
Hilmi C. Altinyazar
3
Abdullah Sivrikaya
4
Ali Ünlü
ORCID: 0000-0002-9991-3939
Anahtar Kelimeler
Acne vulgaris
erythrocyte zinc level
isotretinoin
Vitamin A
zinc
Kurumlar
Selçuk Tip Fakültesi
Konya Turkey
Metrikler
2
Atıf
4
Yazar
5
Anahtar Kelime