Scopus
YÖKSİS Eşleşti
Mild acute kidney injury after pediatric surgery is not-associated with long-term renal dysfunction: A retrospective cohort study
Journal of Clinical Anesthesia · Aralık 2022
YÖKSİS Kayıtları
Mild acute kidney injury after pediatric surgery is not-associated with long-term renal dysfunction: A retrospective cohort study
Journal of Clinical Anesthesia · 2022 SCI
PROFESÖR İBRAHİM ÖZKAN ÖNAL →
Makale Bilgileri
DergiJournal of Clinical Anesthesia
Yayın TarihiAralık 2022
Cilt / Sayfa83
Scopus ID2-s2.0-85140458100
Özet
Background and study objective: Acute kidney injury (AKI) is a sudden deterioration in renal function and is common in pediatric patients undergoing cardiac and non-cardiac surgery. Few studies have investigated the association of postoperative AKI with kidney dysfunction seen long-term and other adverse outcomes in pediatric patients. The study aimed to determine the association between postoperative AKI (mild AKI vs. no AKI and mild AKI vs. moderate-severe AKI) and chronic kidney dysfunction (CKD) seen long-term in pediatric patients undergoing cardiac and non-cardiac major surgery. Design: Restrospective, cohort study. Setting: Tertiary care hospital. Patients: This retrospective cohort study included patients aged 2–18 years who underwent cardiac and non-cardiac major surgery lasting >2 h at the Cleveland Clinic Main Campus between June 2005 and December 2020. Measurements: Postoperative AKI and CKD seen in long-term were defined and staged according to the Kidney Disease: Improving Global Outcomes criteria. Main results: Among 10,597 children who had cardiac and non-cardiac major surgery, 1,302 were eligible. A total of 682 patients were excluded for missing variables and baseline kidney dysfunction and 620 patients were included. The mean age was 11 years, and 307 (49.5%) were female. Postoperative mild AKI was detected in 5.8% of the patients, while moderate-severe AKI was detected in 2.4%. There was no significant difference in CKD seen in long-term between patients with and without postoperative AKI, p = 0.83. The CKD seen in long-term developed in 27.7% of patients with postoperative mild AKI and 33.3% of patients with postoperative moderate and severe AKI. Patients without postoperative AKI had an estimated 1.09 times higher odds of having CKD seen in long-term compared with patients who have postoperative mild AKI (odds ratio [95% CI] 1.09 [0.48,2.52]). Conclusion: In contrast to adult patients, the authors did not find any association between postoperative AKI and CKD seen in long-term in pediatric patients.
Yazarlar (7)
1
Ozkan Onal
ORCID: 0000-0002-5574-1901
2
Surendrasingh Chhabada
3
Xuan Pu
4
Liu Liu
5
Tetsuya Shimada
6
Kurt Ruetzler
7
Alparslan Turan
Anahtar Kelimeler
Acute kidney injury
Chronic kidney disease
Pediatric
Renal function
Kurumlar
Cleveland Clinic Foundation
Cleveland United States
National Defense Medical College Tokorozawa
Tokorozawa Japan
National Hospital Organization Murayama Medical Center
Musashimurayama Japan
Outcomes Research Consortium
Cleveland United States
Selçuk Tip Fakültesi
Konya Turkey
Metrikler
1
Atıf
7
Yazar
4
Anahtar Kelime