The effects of human amniotic membrane and periosteal autograft on tendon healing: Experimental study in rabbits

Journal of Hand Surgery: European Volume · Mayıs 2010

Makale Bilgileri

DergiJournal of Hand Surgery: European Volume

Yayın TarihiMayıs 2010

Cilt / Sayfa35 · 262-268

DOI10.1177/1753193409337961

Scopus ID2-s2.0-77952263751

Özet In this study, the effects of periosteal autograft and human amniotic membrane on tendon healing were compared. Forty-two New Zealand rabbits were divided into three groups. Flexor digitorum fibularis tendons were cut and repaired with a modified Kessler technique and circumferential sutures in all groups. Tendon repair alone was carried out in group 1, tendon repair and application of human amniotic membrane was done in group 2 and tendon repair and application of periosteal autograft was done in group 3. Biomechanical and histopathological examinations were done 2 and 6 weeks postoperatively. Biomechanical examination showed that group 3 was the strongest at weeks 2 and 6. Adhesion, inflammation and new bone formation showed no difference between groups at week 2. However, adhesion formation was found to be less in groups 2 and 3 than group 1 at week 6. The application of periosteal autograft might be useful in repair of tendon injuries. © 2010 The British Society for Surgery of the Hand.