Scopus
YÖKSİS Eşleşti
Development of New Fluorescent Dyes by Using Amine Modified Nanoparticles for Immunostaining
Synthesis and Reactivity in Inorganic, Metal-Organic and Nano-Metal Chemistry · Aralık 2016
YÖKSİS Kayıtları
Development of New Fluorescent Dyes by Using Amine Modified Nanoparticles for Immunostaining
Synthesis and Reactivity in Inorganic, Metal-Organic, and Nano-Metal Chemistry · 2016 SCI-Expanded
PROFESÖR MUSTAFA ÖZMEN →
Development of New Fluorescent Dyes by Using Amine Modified Nanoparticles for Immunostaining
Synthesis and Reactivity in Inorganic, Metal-Organic, and Nano-Metal Chemistry · 2016 SSCI
PROFESÖR ESRA MALTAŞ ÇAĞIL →
Makale Bilgileri
DergiSynthesis and Reactivity in Inorganic, Metal-Organic and Nano-Metal Chemistry
Yayın TarihiAralık 2016
Cilt / Sayfa46 · 1779-1786
Scopus ID2-s2.0-84979879790
Özet
Fluorescent labeling of DNA was studied by using two newly synthesized ligands, which are 4-(2-hydroxybenzylidinamino) benzoic acid (PHBA) and 4-(2-hydroxybenzylidinamino) phthalic acid (PHPA). Their binding capacity to calf-thymus DNA was determined on functionalized superparamagnetic iron oxide nanoparticles (SPIONs). 23.1 µg of DNA was immobilized on 25 mg of nanoparticles. Binding capacity of fluorescent ligands to DNA-APTS-SPIONs was also found as 2.36 µM for PHBA and 1.97 for PHPA at 25 mg of the nanoparticles. Binding of the DNA to the ligands were examined by scanning electron microscopy, transmission electron microscopy, infrared spectroscopy, and confocal microscopy.
Yazarlar (3)
1
Esra Maltas Cagil
2
Mustafa Ozmen
ORCID: 0000-0001-5117-9168
3
H. Ismet Ucan
Anahtar Kelimeler
calf-thymus DNA
fluorescence
ligand
magnetic nanoparticle
Kurumlar
Selçuk Üniversitesi
Selçuklu Turkey