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Preparation of new calix[4]arene-immobilized biopolymers for enhancing catalytic properties of candida rugosa lipase by Sol-Gel encapsulation

Applied Biochemistry and Biotechnology · Ağustos 2013

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YÖKSİS Kayıtları
Preparation of New Calix 4 arene Immobilized Biopolymers for Enhancing Catalytic Properties of Candida rugosa Lipase by Sol Gel Encapsulation
Applied Biochemistry and Biotechnology · 2013 SCI-Expanded
PROFESÖR ELİF ÖZYILMAZ →

Makale Bilgileri

DergiApplied Biochemistry and Biotechnology
Yayın TarihiAğustos 2013
Cilt / Sayfa170 · 1871-1884
Özet The article describes preparation of new calixarene biopolymers consisting of the immobilization of convenience calixarene derivative onto cellulose and chitosan biopolymers, and the encapsulation of these calixarene biopolymers with Candida rugosa lipase within a chemical inert sol-gel supported by polycondensation with tetraethoxysilane and octyltriethoxysilane. The catalytic properties of immobilized lipase were evaluated into model reactions employing the hydrolysis of p-nitrophenylpalmitate and the enantioselective hydrolysis of naproxen methyl esters from racemic prodrugs in aqueous buffer solution/isooctane reaction system. The resolution studies using sol-gel support have observed more improvement in the enantioselectivity of naproxen E = 300 with Cel-Calix-E than with encapsulated lipase without calixarene-based materials. Furthermore, the encapsulated lipase (Cel-Calix-E) was still retained about 39 % of their conversion ratios after the fifth reuse in the enantioselective reaction. © 2013 Springer Science+Business Media New York.

Yazarlar (2)

1
Elif Ozyilmaz
2
Serkan Sayin

Anahtar Kelimeler

Biopolymers Calixarene Enantioselectivity Lipase Naproxen

Kurumlar

Selçuk Üniversitesi
Selçuklu Turkey

Metrikler

22
Atıf
2
Yazar
5
Anahtar Kelime

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