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Effects of ivermectin on cytokine and immunoglobulin levels in sheep

Revista Colombiana de Ciencias Pecuarias · Ekim 2023

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YÖKSİS Kayıtları
Effects of ivermectin on cytokine and immunoglobulin levels in sheep
Revista Colombiana de Ciencias Pecuarias · 2023 SCI-Expanded
DOÇENT MERVE İDER →
Effects of ivermectin on cytokine and immunoglobulin levels in sheep
Rev Colomb Cienc Pecu · 2023 SCI-Expanded
PROFESÖR ENVER YAZAR →
Effects of ivermectin on cytokine and immunoglobulin levels in sheep
Universidad de Antioquia · 2023 SCI-Expanded
PROFESÖR ENVER YAZAR →
Effects of ivermectin on cytokine and immunoglobulin levels in sheep
Revista Colombiana de Ciencias Pecuarias · 2023 CABI
DOÇENT IRMAK DİK →

Makale Bilgileri

DergiRevista Colombiana de Ciencias Pecuarias
Yayın TarihiEkim 2023
Cilt / Sayfa36 · 210-215
Erişim🔓 Açık Erişim
Özet Background: Ivermectin may affect the levels of cytokines and immunoglobulins in sheep, considering that avermectins have an effect on the immune system. Objective: To determine whether ivermectin has an effect on cytokines and immunoglobulins in sheep. Methods: After administration of ivermectin to 10 healthy sheep, sheep-specific interferon-α, tumor necrosis factor-α, interleukin-2, interleukin-6, interleukin-10, immunoglobulin G, immunoglobulin M, and immunoglobulin E levels were measured with an ELISA reader. Results: Significant (p<0.05) fluctuations were detected in interleukin-2 and interleukin-10 levels. Transient increases (p<0.05) were measured in tumor necrosis factor-α and immunoglobulin E levels (p<0.05). Conclusion: Ivermectin may affect immune system parameters in healthy sheep; however, the effects of ivermectin administration on infected sheep should be investigated.

Yazarlar (6)

1
Rahmi Canbar
ORCID: 0000-0001-7100-4437
2
Irmak Dik
ORCID: 0000-0003-2516-9489
3
Muhittin Uslu
ORCID: 0000-0002-9027-4229
4
Merve Ider
ORCID: 0000-0003-2928-5452
5
Mustafa Sedat Arslan
ORCID: 0000-0002-4079-500X
6
E. Yazar

Anahtar Kelimeler

avermectins immunity immunoglobulin E immunoglobulin G immunoglobulin M interferon-α interleukin-10 interleukin-2 interleukin-6 ivermectin sheep tumor necrosis factor-α

Kurumlar

Bozok Üniversitesi
Yozgat Turkey
Necmettin Erbakan Üniversitesi
Meram Turkey
Selçuk Üniversitesi
Selçuklu Turkey