Scopus
🔓 Açık Erişim YÖKSİS Eşleşti
Highly Fluorescent π-Conjugated Azomethines and Divalent Metal Complexes as Antibacterial and Antibiofilm Nominees
Journal of Fluorescence · Ocak 2024
YÖKSİS Kayıtları
Highly Fluorescent π-Conjugated Azomethines and Divalent Metal Complexes as Antibacterial and Antibiofilm Nominees
Journal of Fluorescence · 2024 SCI-Expanded
DOÇENT ASLIHAN YILMAZ OBALI →
Highly Fluorescent π-Conjugated Azomethines and Divalent Metal Complexes as Antibacterial and Antibiofilm Nominees
JOURNAL OF FLUORESCENCE · 2025 SCI-Expanded
DOÇENT ASLIHAN YILMAZ OBALI →
Highly Fluorescent π-Conjugated Azomethines and Divalent Metal Complexes as Antibacterial and Antibiofilm Nominees
Journal of Fluorescence · 2024 SCI-Expanded
DOKTOR ÖĞRETİM ÜYESİ FATİH SEVGİ →
Makale Bilgileri
DergiJournal of Fluorescence
Yayın TarihiOcak 2024
Scopus ID2-s2.0-85200037142
Erişim🔓 Açık Erişim
Özet
π-Conjugated azomethine ligands differing in the naphthalene or phenylmethane-centered core structure and their divalent cobalt, nickel, copper, and zinc metal complexes were prepared and well-characterized by spectral analyses in solid state. Magnetic natures of the complexes were determined by magnetic susceptibility measurements in solid-state. Their remarkable photophysical characteristics were recorded by Uv–vis and Fluorescence spectroscopic techniques. At their excitation wavelenght of 265 nm, all molecules exhibited triple fluorescence emission bands with promising intensities above 673 nm in near infra-red region. Antibacterial and antibiofilm activities of the π-conjugated azomethines are promising for potential applications in medical and healthcare settings. Hence, the antibacterial/antibiofilm activity of the π-conjugated azomethine ligands and their metal complexes against some clinically important bacteria namely Staphylococcus aureus (MSSA), Methicillin-resistant Staphylococcus aureus (MRSA), Staphylococcus epidermidis, Escherichia coli, Pseudomonas aeruginosa and Proteus mirabilis was investigated, and the obtained results have shown that the ligands and complexes had a remarkable antibacterial effect, especially on Proteus mirabilis. Metal complexes have been found to have a significant inhibitory effect on biofilm formation by MRSA, MSSA, and P. mirabilis compared to ligands. The copper (II) complex of ligand-2 showed the highest inhibition percentage, significantly reducing biofilm formation for MRSA and MSSA. Furthermore, cobalt (II) complexes of the ligands selectively inhibited the growth of the opportunistic pathogen P. mirabilis biofilms, indicating that metal complexes might be a good choice for future antibiofilm studies.
Yazarlar (5)
1
Şeyma Nur Ural Baydeniz
2
H. Ismet Ucan
3
F. Sevgi
4
I. Obali
5
Aslihan Yilmaz Obali
Anahtar Kelimeler
Antibacterial
Antibiofilm
Fluorescent
Hydroxy-substitution
MRSA
Proteus mirabilis
Schiff base
Kurumlar
Selçuk Üniversitesi
Selçuklu Turkey