Scopus
🔓 Açık Erişim YÖKSİS DOI Eşleşti
SJR Q2
Screening the in vitro antioxidant, antimicrobial, anticholinesterase, antidiabetic activities of endemic Achillea cucullata (Asteraceae) ethanol extract
South African Journal of Botany · Ocak 2019
YÖKSİS Kayıtları
Screening the in vitro antioxidant, antimicrobial, anticholinesterase, antidiabetic activities of endemic Achillea cucullata (Asteraceae) ethanol extract
South African Journal of Botany · 2019 SCI-Expanded
Prof. Dr. NURANİYE ERUYGUR →
YÖKSİS Kayıtları — ISSN Eşleşmesi
Novel perspectives on two Digitalis species: Phenolic profile, bioactivity, enzyme inhibition, and toxicological evaluation
2017 ISSN: 02546299 SCI-Expanded
Prof. Dr. ABDURRAHMAN AKTÜMSEK →
Screening the in vitro antioxidant, antimicrobial, anticholinesterase, antidiabetic activities of endemic Achillea cucullata (Asteraceae) ethanol extract
2019 ISSN: 0254-6299 SCI-Expanded
Prof. Dr. NURANİYE ERUYGUR →
Chemical profile, antioxidant properties and enzyme inhibitory effects of the root extracts of selected Potentilla species
2018 ISSN: 0254-6299 SCI-Expanded
Prof. Dr. GÖKHAN ZENGİN →
Phytochemical characterization and antioxidant activities of the fruit extracts of several Crataegus taxa
2019 ISSN: 0254-6299 SCI-Expanded
Prof. Dr. YÜKSEL KAN →
Gundelia rosea seed: Evaluation of biopharmaceutical potentialand bioactive composition
2019 ISSN: 0254-6299 SCI-Expanded
Prof. Dr. GÖKHAN ZENGİN →
Effect of Viscum album L. ssp. austriacum (WİESP.) Vollman on metronidazole resistant and sensitive strains of Trichomonas vaginalis
2019 ISSN: 0254-6299 SCI
Prof. Dr. NURANİYE ERUYGUR →
Effect of cold-press and soxhlet extraction on fatty acids, tocopherolsand sterol contents of the Moringa seed oils
2019 ISSN: 0254-6299 SCI-Expanded
Prof. Dr. MEHMET MUSA ÖZCAN →
Gundelia rosea seed: Evaluation of biopharmaceutical potential and bioactive composition
2019 ISSN: 0254-6299 SCI-Expanded
Prof. Dr. GÖKHAN ZENGİN →
Gundelia rosea seed: Evaluation of biopharmaceutical potential and bioactive composition
2019 ISSN: 0254-6299 SCI-Expanded Q2
Prof. Dr. GÖKHAN ZENGİN →
Enzyme inhibitory and antioxidant properties of six mushroom species from the Agaricaceae family
2019 ISSN: 02546299 SCI-Expanded
Prof. Dr. GÖKHAN ZENGİN →
In vitro tyrosinase inhibitory and antioxidant potential of Consolida orientalis, Onosma isauricum and Spartium junceum from Turkey
2019 ISSN: 0254-6299 SCI
Prof. Dr. GÖKHAN ZENGİN →
Chemical profile, antioxidant properties and enzyme inhibitory effects of the root extracts of selected Potentilla species
2019 ISSN: 0254-6299 SCI
Prof. Dr. GÖKHAN ZENGİN →
Chemical profile, antioxidant properties and enzyme inhibitory effects of the root extracts of selected Potentilla species
2019 ISSN: 0254-6299 SCI-Expanded
Prof. Dr. GÖKHAN ZENGİN →
Enzyme inhibitory and antioxidant properties of six mushroom species from the Agaricaceae family
2019 ISSN: 0254-6299 SCI-Expanded
Prof. Dr. GÖKHAN ZENGİN →
Biopharmaceutical potential, chemical profile and in silico study of the seagrass– Syringodium isoetifolium (Asch.) Dandy
2019 ISSN: 0254-6299 SCI-Expanded
Prof. Dr. GÖKHAN ZENGİN →
Gundelia rosea seed: Evaluation of biopharmaceutical potential and bioactive composition
2019 ISSN: 0254-6299 SCI-Expanded
Prof. Dr. GÖKHAN ZENGİN →
In vitro tyrosinase inhibitory and antioxidant potential of Consolida orientalis, Onosma isauricum and Spartium junceum from Turkey
2019 ISSN: 0254-6299 SCI-Expanded
Prof. Dr. GÖKHAN ZENGİN →
Chemical profile, antioxidant properties and enzyme inhibitory effects of the root extracts of selected Potentilla species
2019 ISSN: 0254-6299 SCI-Expanded
Prof. Dr. GÖKHAN ZENGİN →
Asphodeline cilicica Tuzlaci: From the plant to its most active part extract and its broad bioactive properties
2019 ISSN: 0254-6299 SCI-Expanded
Prof. Dr. ABDURRAHMAN AKTÜMSEK →
In vitro plant regeneration, and jasmonic acid induced bioactive chemical accumulations in two Hypericum species from Turkey.
2020 ISSN: 0254-6299 SCI-Expanded
Prof. Dr. ERTAN SAİT KURTAR →
Makale Bilgileri
ISSN02546299
Yayın TarihiOcak 2019
Cilt / Sayfa120 · 141-145
Scopus ID2-s2.0-85046148840
Erişim🔓 Açık Erişim
Özet
The Achillea genus belongs to the Asteraceae family, which is mostly found in the northern hemisphere and is comprised of 115 species in the world. In Turkish flora, there are 52 species and 58 taxa, among them half of which are recorded as endemic. To the best of our knowledge, there has been no biological activity studied in this species until now, with the exception of one study of the antimicrobial activity of certain essential oils. This study focused primarily on the determination of antioxidant, antimicrobial, and enzyme-inhibition activity of aqueous ethanol extract of Turkish endemic Achillea cucullata by in vitro methods. The extract exhibited DPPH radical scavenging activity with an IC50 value of 132.55 ± 0.026 μg/mL, the total phenol content was 53.807 ± 0.059 (mg GAE/g), and the total flavonoid content was 21.372 ± 0.026 (mg QE/g), on the dry-weight basis. Antimicrobial activity was evaluated by a micro-dilution method focused on five microorganisms; two Gram-positive [Staphylococcus aureus (ATCC 29213) and Enterococcus faecalis (ATCC 29212)], two Gram-negative [Pseudomonas aeruginosa (ATCC 27853) and Escherichia coli (ATCC 25922)], and one fungal strain [Candida albicans (ATCC 10231)]. Results show that the MIC value for the tested microorganism was higher than 5 mg/mL. In this work, acetylcholinesterase (AChE), butyrylcholinesterase (BChE), and α-glucosidase enzymes were strongly inhibited by the A. cucullata extract, and the IC50 values for these enzymes were 2.4 μg/mL, 0.26 μg/mL, and 24.75 μg/mL, respectively. Certain acetylcholinesterase inhibitors have been used for treatment of Alzheimer's disease in the past. α-Glucosidase inhibitors are strong drug candidates, as well as potential functional food agents, for deferring the postprandial absorbency of glucose.
Yazarlar (6)
1
Nuraniye Eruygur
2
U. M. Koçyiğit
3
P. Taslimi
4
Mehmet Ataş
5
Mehmet Tekin
6
Gülçin
Anahtar Kelimeler
Achillea cucullata
Anticholinesterase activity
Antidiabetic activity
Antimicrobial activity
Antioxidant activity
Kurumlar
Atatürk Üniversitesi
Erzurum Turkey
Cumhuriyet Üniversitesi
Sivas Turkey
Selçuk Üniversitesi
Selçuklu Turkey
Trakya Üniversitesi
Edirne Turkey
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Scimago Dergi (ISSN Eşleşmesi)
South African Journal of Botany
Q2
SJR Skoru0,558
H-Index92
YayıncıElsevier B.V.
ÜlkeNetherlands
Plant Science (Q2)
Metrikler
217
Atıf
6
Yazar
5
Anahtar Kelime