Scopus
🔓 Açık Erişim YÖKSİS DOI Eşleşti
SJR Q2
Effect of Viscum album L. ssp. austriacum (WİESP.) Vollman on metronidazole resistant and sensitive strains of Trichomonas vaginalis
South African Journal of Botany · Eylül 2019
YÖKSİS Kayıtları
Effect of Viscum album L. ssp. austriacum (WİESP.) Vollman on metronidazole resistant and sensitive strains of Trichomonas vaginalis
South African Journal of Botany · 2019 SCI
Prof. Dr. NURANİYE ERUYGUR →
YÖKSİS Kayıtları — ISSN Eşleşmesi
Novel perspectives on two Digitalis species: Phenolic profile, bioactivity, enzyme inhibition, and toxicological evaluation
2017 ISSN: 02546299 SCI-Expanded
Prof. Dr. ABDURRAHMAN AKTÜMSEK →
Screening the in vitro antioxidant, antimicrobial, anticholinesterase, antidiabetic activities of endemic Achillea cucullata (Asteraceae) ethanol extract
2019 ISSN: 0254-6299 SCI-Expanded
Prof. Dr. NURANİYE ERUYGUR →
Chemical profile, antioxidant properties and enzyme inhibitory effects of the root extracts of selected Potentilla species
2018 ISSN: 0254-6299 SCI-Expanded
Prof. Dr. GÖKHAN ZENGİN →
Phytochemical characterization and antioxidant activities of the fruit extracts of several Crataegus taxa
2019 ISSN: 0254-6299 SCI-Expanded
Prof. Dr. YÜKSEL KAN →
Gundelia rosea seed: Evaluation of biopharmaceutical potentialand bioactive composition
2019 ISSN: 0254-6299 SCI-Expanded
Prof. Dr. GÖKHAN ZENGİN →
Effect of Viscum album L. ssp. austriacum (WİESP.) Vollman on metronidazole resistant and sensitive strains of Trichomonas vaginalis
2019 ISSN: 0254-6299 SCI
Prof. Dr. NURANİYE ERUYGUR →
Effect of cold-press and soxhlet extraction on fatty acids, tocopherolsand sterol contents of the Moringa seed oils
2019 ISSN: 0254-6299 SCI-Expanded
Prof. Dr. MEHMET MUSA ÖZCAN →
Gundelia rosea seed: Evaluation of biopharmaceutical potential and bioactive composition
2019 ISSN: 0254-6299 SCI-Expanded
Prof. Dr. GÖKHAN ZENGİN →
Gundelia rosea seed: Evaluation of biopharmaceutical potential and bioactive composition
2019 ISSN: 0254-6299 SCI-Expanded Q2
Prof. Dr. GÖKHAN ZENGİN →
Enzyme inhibitory and antioxidant properties of six mushroom species from the Agaricaceae family
2019 ISSN: 02546299 SCI-Expanded
Prof. Dr. GÖKHAN ZENGİN →
In vitro tyrosinase inhibitory and antioxidant potential of Consolida orientalis, Onosma isauricum and Spartium junceum from Turkey
2019 ISSN: 0254-6299 SCI
Prof. Dr. GÖKHAN ZENGİN →
Chemical profile, antioxidant properties and enzyme inhibitory effects of the root extracts of selected Potentilla species
2019 ISSN: 0254-6299 SCI
Prof. Dr. GÖKHAN ZENGİN →
Chemical profile, antioxidant properties and enzyme inhibitory effects of the root extracts of selected Potentilla species
2019 ISSN: 0254-6299 SCI-Expanded
Prof. Dr. GÖKHAN ZENGİN →
Enzyme inhibitory and antioxidant properties of six mushroom species from the Agaricaceae family
2019 ISSN: 0254-6299 SCI-Expanded
Prof. Dr. GÖKHAN ZENGİN →
Biopharmaceutical potential, chemical profile and in silico study of the seagrass– Syringodium isoetifolium (Asch.) Dandy
2019 ISSN: 0254-6299 SCI-Expanded
Prof. Dr. GÖKHAN ZENGİN →
Gundelia rosea seed: Evaluation of biopharmaceutical potential and bioactive composition
2019 ISSN: 0254-6299 SCI-Expanded
Prof. Dr. GÖKHAN ZENGİN →
In vitro tyrosinase inhibitory and antioxidant potential of Consolida orientalis, Onosma isauricum and Spartium junceum from Turkey
2019 ISSN: 0254-6299 SCI-Expanded
Prof. Dr. GÖKHAN ZENGİN →
Chemical profile, antioxidant properties and enzyme inhibitory effects of the root extracts of selected Potentilla species
2019 ISSN: 0254-6299 SCI-Expanded
Prof. Dr. GÖKHAN ZENGİN →
Asphodeline cilicica Tuzlaci: From the plant to its most active part extract and its broad bioactive properties
2019 ISSN: 0254-6299 SCI-Expanded
Prof. Dr. ABDURRAHMAN AKTÜMSEK →
In vitro plant regeneration, and jasmonic acid induced bioactive chemical accumulations in two Hypericum species from Turkey.
2020 ISSN: 0254-6299 SCI-Expanded
Prof. Dr. ERTAN SAİT KURTAR →
Makale Bilgileri
ISSN02546299
Yayın TarihiEylül 2019
Cilt / Sayfa125 · 81-85
Scopus ID2-s2.0-85069004188
Erişim🔓 Açık Erişim
Özet
Trichomonas vaginalis (T. vaginalis) is a parasitic protozoan that causes trichomoniasis. Metronidazole is the standard treatment for trichomoniasis; however, metronidazole-resistant strains are implicated in an increasing number of refractory cases. Therefore, the discovery of an antiprotozoal agent that is effective on metronidazole-resistant T. vaginalis will prevent major health problems. In this study, we investigated the antiprotozoal effects of leaf, fruit and body extracts of Viscum album L. ssp. austriacum (VA) on metronidazole-resistant and -sensitive T. vaginalis protozoa. The VA used in our study was collected from 20 different pine trees in September and October. The leaves, fruits and bodies of the VA plants collected were separated and dry extracts were obtained with hexane, chloroform, n-butanol, ethyl acetate and water. The minimum lethal dose (MLD) of the metronidazole-sensitive strain, T. vaginalis ATCC50148 and the metronidazole-resistant strain, T. vaginalis ATCC50143 against metronidazole was tested in comparison with the plant extracts. In addition, GC–MS analysis was performed on the plant extracts that has antiprotozoal effects. Some of the substances identified from GC–MS analysis were purchased commercially and their antiprotozoal effects were further investigated. The VA leaf and fruit ethyl acetate extracts and body butanol extract had the most effect on T. vaginalis. GC–MS qualitative analysis detected 2,4-heptadienal, 3-methylsilane, and 2-methylfuran. Of these substances, only 2-methylfuran was found to be effective on T. vaginalis strains. Our findings suggest that the 2-methylfuran found in Viscum album L. ssp. austriacum extracts may be an alternative chemotherapeutic agent to metronidazole.
Yazarlar (3)
1
Hülya Ozpinar
ORCID: 0000-0001-8154-0874
2
Necati Ozpinar
ORCID: 0000-0002-7317-885X
3
Nuraniye Eruygur
Anahtar Kelimeler
Metronidazole
Trichomonas vaginalis
Viscum album
Kurumlar
Cumhuriyet Üniversitesi
Sivas Turkey
Selçuk Üniversitesi
Selçuklu Turkey
Scimago Dergi (ISSN Eşleşmesi)
South African Journal of Botany
Q2
SJR Skoru0,558
H-Index92
YayıncıElsevier B.V.
ÜlkeNetherlands
Plant Science (Q2)
Metrikler
6
Atıf
3
Yazar
3
Anahtar Kelime