Scopus
🔓 Açık Erişim YÖKSİS DOI Eşleşti
SJR Q4
BIOLOGICAL ACTIVITY EVALUATION OF THREE Hypericum L. SPECIES
Trakya University Journal of Natural Sciences · Ekim 2022
YÖKSİS Kayıtları
Biological activity evaluation of three Hypericum species wild growing in Sivas province of Turkey
Trakya University Journal of Natural Sciences · 2022 Web of Science - Emerging Sources Citation Index (ESCI)
Prof. Dr. NURANİYE ERUYGUR →
YÖKSİS Kayıtları — ISSN Eşleşmesi
EVALUATION OF THE ANTIVIRAL ACTIVITY OF Ballota glandulosissima Hub.-Mor. Patzak EXTRACTS AGAINST RESPIRATORY SYNCYTIAL VIRUS (RSV)
2019 ISSN: 2147-0294 Emerging Sources Citation Index, TR Dizin
Prof. Dr. HASAN HÜSEYİN DOĞAN →
NOTES ON Arabis kaynakiae Daşkın (Brassicaceae), A CRITICALLY ENDANGERED SPECIES ENDEMIC TO TURKEY
2020 ISSN: 2147-0294 TR DİZİN
Doç. Dr. EMRAH ŞİRİN →
THE MYCOBIOTA OF SAMANLI MOUNTAINS IN TURKEY
2021 ISSN: 2147-0294 Emerging Sorches Sciences index
Prof. Dr. HASAN HÜSEYİN DOĞAN →
THE ANTI HRSV ACTIVITY OF Ferula halophila Peşmen AQUEOUS AND METHANOL EXTRACT BY MTT ASSAY
2021 ISSN: 2147-0294 Emerging Sorches Sciences index
Prof. Dr. HASAN HÜSEYİN DOĞAN →
A NEW TRUFFLE SPECIES ADDITION, TUBER MACROSPORUM, TO TURKISH MYCOTA
2021 ISSN: 2147-0294 Emerging Sorches Sciences index
Prof. Dr. HASAN HÜSEYİN DOĞAN →
Biological activity evaluation of three Hypericum species wild growing in Sivas province of Turkey
2022 ISSN: 2147-0294 Web of Science - Emerging Sources Citation Index (ESCI)
Prof. Dr. NURANİYE ERUYGUR →
Natural Treatment Approaches For Varicose Veins: A Brief Review Of The Literature
2024 ISSN: 2147-0294 ESCI
Arş. Gör. TUĞSEN BÜYÜKYILDIRIM →
Makale Bilgileri
ISSN21470294
Yayın TarihiEkim 2022
Cilt / Sayfa23 · 125-134
Scopus ID2-s2.0-85205591066
Erişim🔓 Açık Erişim
Özet
This study was performed in order to evaluate in vitro antioxidant, anti-Trichomonas vaginalis, antimicrobial and cytotoxic activities of methanol extracts of aerial parts of Hypericum perforatum L., H. thymbrifolium Boiss. & Noë and H. thymopsis Boiss. The antioxidant activity of methanol extracts was tested with 2,2-diphenyl-1-picrylhydrazyl (DPPH), 2,2′-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) radical scavenging and iron chelating assays. The total phenol and flavonoid contents were also determined spectrophotometrically. Cytotoxicity and apoptosis were evaluated on MCF-7 breast cancer and PC3 prostate cancer cell line. Antimicrobial activities were evaluated by the microdilution method on the bacterial strains Staphylococcus aureus (ATCC 29213), Enterococcus faecalis (ATCC 29212), Pseudomonas aeruginosa (ATCC 27853) Escherichia coli (ATCC 25922) and the fungal strain Candida albicans (ATCC 10231). All extracts demonstrated cytotoxic activity on PC3 prostat cancer cell line with a concentration dependent manner, while H. thymopsis extract was the most active against cancer cell growth. The obtained results of the present study revealed that the methanol extract of H. perforatum, H. thymbrifolium and H. thymopsis have significant antioxidant and cytotoxic activities. The results provided the basic research data for further phytochemical and biological activity guided investigations on these species for identication and isolation of potential drug active compounds.
Yazarlar (6)
1
Nuraniye Eruygur
2
Necati Ozpinar
ORCID: 0000-0002-7317-885X
3
Hülya Ozpinar
ORCID: 0000-0001-8154-0874
4
Mehmet Ataş
5
Mehmet Tekin
ORCID: 0000-0003-1837-7917
6
Ozge Çevik
ORCID: 0000-0002-9325-3757
Anahtar Kelimeler
Antimicrobial
Antioxidant
Anti-Trichomonas
Cytotoxicity
Hypericum perforatum
Hypericum thymbrifolium
Hypericum thymopsis
Kurumlar
Aydin Adnan Menderes University
Aydin Turkey
Cumhuriyet Üniversitesi
Sivas Turkey
Mustafa Kemal Üniversitesi
Antakya Turkey
Selçuk Üniversitesi
Selçuklu Turkey
Trakya Üniversitesi
Edirne Turkey
Scimago Dergi (ISSN Eşleşmesi)
Trakya University Journal of Natural Sciences
Q4
OA
SJR Skoru0,225
H-Index7
ÜlkeTurkey
Biochemistry, Genetics and Molecular Biology (miscellaneous) (Q4)
Molecular Biology (Q4)
Metrikler
2
Atıf
6
Yazar
7
Anahtar Kelime