Scopus
YÖKSİS Eşleşti
Novel copper(II) complexes of p-tert-butylcalix[4]arene diamide derivatives: Synthesis, antimicrobial and DNA cleavage activities
Supramolecular Chemistry · Nisan 2015
YÖKSİS Kayıtları
Novel copper II complexes of p tert butylcalix 4 arene diamide derivatives synthesis antimicrobial and DNA cleavage activities
Supramolecular Chemistry · 2015 SCI-Expanded 1 atıf
PROFESÖR AYDAN YILMAZ →
Novel copper II complexes of p tert butylcalix 4 arene diamide derivatives synthesis antimicrobial and DNA cleavage activities
Supramolecular Chemistry · 2015 SCI-Expanded 1 atıf
PROFESÖR EMİNE ARSLAN →
Novel copper II complexes of p tert butylcalix 4 arene diamide derivatives Synthesis Antimicrobial and DNA cleavage activities
Supramolecular Chemistry · 2015 SCI
PROFESÖR ÜLKÜ AKPINAR →
Makale Bilgileri
DergiSupramolecular Chemistry
Yayın TarihiNisan 2015
Cilt / Sayfa27 · 255-267
Scopus ID2-s2.0-84941043753
Özet
In this study, two new Cu(II) complexes of p-tert-butylcalix[4]arene amide derivatives (8, 9) have been synthesised and investigated their DNA cleavage and antimicrobial activities. On the basis of spectral studies, a smaller distortion of square planar geometry has been proposed for both of the copper(II) complexes. The DNA cleavage studies show that the ligands are not efficacious, whereas the complexes have high activity. Futhermore, in order to determine the site of DNA cleavage, the DNA interactions of these compounds were investigated with some restriction enzymes. In addition, all synthesised compounds were screened for antimicrobial activities against some bacteria and for antifungal activities against yeast strains. The results showed that ethyl ester and furfuryl amide derivatives of the calixarenes are more efficient than other compounds against tested bacteria. However, complexes have not been effective. In case of DNA interaction studies, compounds were very effective against plasmid DNA.
Yazarlar (6)
1
Seyda Cigdem Ozkan
2
Aydan Yilmaz
3
Emine Arslan
4
Leyla Açik
5
Ulku Sayin
6
Elif Gülbahçe Mutlu
Anahtar Kelimeler
antimicrobial
calix[4]arene
copper(II) complex
DNA cleavage activity
EPR
restriction enzyme
Kurumlar
Gazi Üniversitesi
Ankara Turkey
Selçuk Üniversitesi
Selçuklu Turkey
Metrikler
14
Atıf
6
Yazar
6
Anahtar Kelime