Scopus
YÖKSİS DOI Eşleşti
SJR Q4
Laboratory Diagnosis of Pediatric Herpesvirus Infections of the Central Nervous System by a Multiplex Polymerase Chain Reaction Assay and Intrathecal Antibodies
Journal of Pediatric Infectious Diseases · Ocak 2018
YÖKSİS Kayıtları
Laboratory Diagnosis of Pediatric Herpesvirus Infections of the Central Nervous System by a Multiplex Polymerase Chain Reaction Assay and Intrathecal Antibodies
Journal of Pediatric Infectious Diseases · 2018 SCI-Expanded
Prof. Dr. SİBEL YAVRU →
YÖKSİS Kayıtları — ISSN Eşleşmesi
Independent Predictors of Severity and Hospitalization in Acute Bronchiolitis: Neutrophil/Lymphocyte Ratio and Mean Platelet Volume
2018 ISSN: 1305-7707 SCI-Expanded
Prof. Dr. RESUL YILMAZ →
Benign Acute Childhood Myositis Associated with Influenza A (H1N1) Virus Infection: Evaluation of 22 Cases
2019 ISSN: 1305-7707 SCI-Expanded
Prof. Dr. ALAADDİN YORULMAZ →
Diagnostic Value of Clinical and Laboratory Findings in Childhood Meningitis
2020 ISSN: 1305-7707 SCI-Expanded
Prof. Dr. MELİKE EMİROĞLU →
Pulmonary Hypertension in Children with Lower Respiratory Tract Infections in the Konya Province of Turkey
2020 ISSN: 1305-7707 SCI-Expanded
Prof. Dr. AHMET SERT →
Analysis of Pediatric Intensive Care Unit Admissions for Crimean–Congo Hemorrhagic Fever in Turkey
2020 ISSN: 1305-7707 SCI-Expanded Q4
Prof. Dr. RESUL YILMAZ →
Reasons for Vaccine Rejection in 0 to 2 Years Old Children Registered to Family Health Centers in Konya
2021 ISSN: 1305-7707 SCI-Expanded Q4
Prof. Dr. FATİH KARA →
Investigation of Antibiotic Susceptibility and Virulence Genes in Escherichia coli Strains Isolated from Blood and Urine Samples
2022 ISSN: 1305-7707 SCI-Expanded Q4
Prof. Dr. HATİCE TÜRK DAĞI →
Laboratory Diagnosis of Pediatric Herpesvirus Infections of the Central Nervous System by a Multiplex Polymerase Chain Reaction Assay and Intrathecal Antibodies
2018 ISSN: 1305-7707 SCI-Expanded
Prof. Dr. SİBEL YAVRU →
Investigation of Antibiotic Susceptibility and Virulence Genes in Escherichia coli Strains Isolated from Blood and Urine Samples
2022 ISSN: 1305-7707 SCI-Expanded
Prof. Dr. UĞUR ARSLAN →
Ophthalmic Manifestations of Multisystem Inflammatory Syndrome in Children
2023 ISSN: 1305-7707 SCI-Expanded Q4
Doç. Dr. GÜLSÜM ALKAN →
Ophthalmic Manifestations of Multisystem Inflammatory Syndrome in Children
2023 ISSN: 1305-7707 SCI-Expanded Q4
Prof. Dr. AHMET SERT →
Ophthalmic Manifestations of Multisystem Inflammatory Syndrome in Children
2023 ISSN: 1305-7707 SCI-Expanded Q4
Prof. Dr. BANU BOZKURT →
Ophthalmic Manifestations of Multisystem Inflammatory Syndrome in Children
2023 ISSN: 1305-7707 SCI-Expanded Q4
Dr. Öğr. Üyesi ŞULE ACAR DUYAN →
Evaluation of Clinical and Laboratory Findings of Sinusitis Complications in Children
2024 ISSN: 1305-7707 SCI-Expanded Q4
Doç. Dr. GÜLSÜM ALKAN →
Evaluation of Clinical and Laboratory Findings of Sinusitis Complications in Children
2024 ISSN: 1305-7707 SCI-Expanded Q4
Prof. Dr. MEHMET ÖZTÜRK →
Evaluation of Clinical and Laboratory Findings of Sinusitis Complications in Children
2024 ISSN: 1305-7707 SCI-Expanded
Dr. Öğr. Üyesi MUHAMMET FATİH GÖKMEN →
Ophthalmic Manifestations of Multisystem Inflammatory Syndrome in Children
2023 ISSN: 1305-7707 SCI-Expanded
Dr. Öğr. Üyesi ŞULE ACAR DUYAN →
Treatment Method of Hydatid Disease in Children, which is A Problem in Developing Countries
2025 ISSN: 1305-7707 SCI-Expanded
Dr. Öğr. Üyesi MEHMET SARIKAYA →
Makale Bilgileri
ISSN13057707
Yayın TarihiOcak 2018
Cilt / Sayfa13 · 178-184
Scopus ID2-s2.0-85044583352
Özet
Introduction Central nervous system (CNS) viral infections are a serious problem requiring accurate diagnosis and treatment. Human herpesviruses (HHVs) are an important cause of these infections. Recent research has focused on new diagnostic methods allowing accurate and rapid identification of viral infections because there are still diagnostic difficulties for these infections. This study was done to determine the etiologic role of human herpes viruses and to obtain information that will contribute to the diagnostic algorithm in suspected cases of viral encephalitis or aseptic meningitis. Materials and Methods In our study, herpes simplex virus (HSV)-1, HSV-2, varicella zoster virus (VZV), cytomegalovirus (CMV), Epstein-Barr virus (EBV), and HHV-6 DNA was detected in the cerebrospinal fluid (CSF) by multiplex polymerase chain reaction (PCR) and virus-specific immunoglobulin G (IgG) antibodies in CSF and serum by EIA in pediatric encephalitis/meningitis cases. Results HSV-1 and VZV were detected in 5 and 3.3% of aseptic meningitis cases, respectively, but no encephalitis cases. Other viruses were not identified as etiologic agents. The seroprevalences were determined as 72.4, 34.3, 81.9, 93.3, 88.6, and 80.9%, respectively for HSV-1, HSV-2, VZV, CMV, EBV, and HHV-6. The performance of specific IgG CSF/serum antibody index (AI) was not satisfactory. Conclusion Our study indicates that the multiplex PCR method is the most suitable for the diagnosis of CNS infections caused by HHVs. However, due to the high cost of the PCR method, the positive results of the specific AI may be significant, but the negative results are unreliable, especially in limited health care facilities.
Yazarlar (3)
1
Bahadir Feyzioglu
2
Sibel Yavru
3
Mehmet Ozdemir
Anahtar Kelimeler
antibody index
human herpes viruses
multiplex PCR
Kurumlar
Necmettin Erbakan Üniversitesi
Meram Turkey
Selçuk Üniversitesi
Selçuklu Turkey
Scimago Dergi (ISSN Eşleşmesi)
Journal of Pediatric Infectious Diseases
Q4
SJR Skoru0,142
H-Index17
YayıncıIOS Press BV
ÜlkeNetherlands
Infectious Diseases (Q4)
Pediatrics, Perinatology and Child Health (Q4)
Metrikler
2
Atıf
3
Yazar
3
Anahtar Kelime