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Scopus 🔓 Açık Erişim YÖKSİS DOI Eşleşti SJR Q3

Nerium oleander distillate improves fat and glucose metabolism in high-fat diet-fed streptozotocin-induced diabetic rats

International Journal of Endocrinology · Aralık 2012

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YÖKSİS Kayıtları
Nerium oleander Distillate Improves Fat and Glucose Metabolism in High Fat Diet Fed Streptozotocin Induced Diabetic Rats
International Journal of Endocrinology · 2012 SCI-Expanded 10 atıf
Prof. Dr. KAMİL ÜNEY →
Nerium oleander Distillate Improves Fat and Glucose Metabolism in High Fat Diet Fed Streptozotocin Induced Diabetic Rats
International Journal of Endocrinology · 2012 SCI-Expanded 10 atıf
Prof. Dr. AHMET LEVENT BAŞ →
Nerium oleander Distillate Improves Fat and Glucose Metabolism in High Fat Diet Fed Streptozotocin Induced Diabetic Rats
International Journal of Endocrinology · 2012 SCI-Expanded
Prof. Dr. AHMET LEVENT BAŞ →
YÖKSİS ISSN Eşleşmesi

Bu dergide (ISSN eşleşmesi) kurumun 3 kaydı bulundu.

YÖKSİS Kayıtları — ISSN Eşleşmesi
Nerium oleander Distillate Improves Fat and Glucose Metabolism in High Fat Diet Fed Streptozotocin Induced Diabetic Rats
2012 ISSN: 1687-8337 SCI-Expanded
Prof. Dr. AHMET LEVENT BAŞ →
Nerium oleander distillate improves fat and glucose metabolism in high fat diet fed streptozotocin induced diabetic rats
2012 ISSN: 1687-8337 SCI
Prof. Dr. AHMET LEVENT BAŞ →
Nerium oleander Distillate Improves Fat and Glucose Metabolism in High Fat Diet Fed Streptozotocin Induced Diabetic Rats
2012 ISSN: 1687-8337 SCI-Expanded 10 atıf
Prof. Dr. KAMİL ÜNEY →

Makale Bilgileri

Dergi International Journal of Endocrinology
ISSN16878337
Yayın TarihiAralık 2012
Cilt / Sayfa2012
DOI10.1155/2012/947187
Scopus ID2-s2.0-84871380149
Erişim🔓 Açık Erişim
Özet Diabetes was induced by intraperitoneal injection of streptozotocin (35 mg/kg bw) in all rats of five groups after being fed for 2 weeks high-fat diet. Type 2 diabetic Nerium-oleander- (NO-) administered groups received the NO distillate at a dose of 3.75, 37.5, and 375 g/0.5 mL of distilled water (NO-0.1, NO-1, NO-10, resp.); positive control group had 0.6 mg glibenclamide/kg bw/d by gavage daily for 12 weeks. Type 2 diabetic negative control group had no treatment. NO distillate administration reduced fasting blood glucose, HbA1c, insulin resistance, total cholesterol, low density lipoprotein, atherogenic index, triglyceride-HDL ratio, insulin, and leptin levels. Improved beta cell function and HDL concentration were observed by NO usage. HDL percentage in total cholesterol of all NO groups was similar to healthy control. NO-10 distillate enhanced mRNA expressions of peroxisome proliferator-activated- receptor- (PPAR-) α, β, and γ in adipose tissue and PPAR-α-γ in liver. The findings from both in vivo and in vitro studies suggest that the considerable beneficial effect of NO distillate administration at a dose of 375 g/0.5 mL of distilled water may offer new approaches to treatment strategies that target both fat and glucose metabolism in type 2 diabetes. © 2012 Ahmet Levent Bas et al.

Yazarlar (5)

1
A. L. Baş
2
Sule Demirci
3
Nuray Yazihan
ORCID: 0000-0003-1237-8468
4
Kamil Üney
ORCID: 0000-0002-8674-4873
5
Ezgi Ermis Kaya

Kurumlar

Ankara Üniversitesi
Ankara Turkey
Burdur Mehmet Akif Ersoy Üniversitesi
Burdur Turkey
Selçuk Üniversitesi
Selçuklu Turkey
Scimago Dergi (ISSN Eşleşmesi)
International Journal of Endocrinology
Q3 OA
SJR Skoru0,667
H-Index84
YayıncıJohn Wiley and Sons Ltd
ÜlkeUnited States
Endocrine and Autonomic Systems (Q3)
Endocrinology (Q3)
Endocrinology, Diabetes and Metabolism (Q3)
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Metrikler

34
Atıf
5
Yazar

Sistemimizdeki Yazarlar

AB
AHMET LEVENT BAŞ
Prof. Dr.

Hızlı Erişim

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