Scopus
YÖKSİS Eşleşti
Effects of glyphosate on juvenile rainbow trout (Oncorhynchus mykiss): Transcriptional and enzymatic analyses of antioxidant defence system, histopathological liver damage and swimming performance
Ecotoxicology and Environmental Safety · Ocak 2015
YÖKSİS Kayıtları
Effects of glyphosate on juvenile rainbow trout Oncorhynchus mykiss Transcriptional and enzymatic analyses of antioxidant defence system histopathological liver damage and swimming performance
Ecotoxicology and Environmental Safety · 2015 SCI-Expanded
PROFESÖR ERTAN ORUÇ →
Makale Bilgileri
DergiEcotoxicology and Environmental Safety
Yayın TarihiOcak 2015
Cilt / Sayfa111 · 206-214
Scopus ID2-s2.0-84908688769
Özet
This study aims to determine the effect of glyphosate on the transcriptional and enzymatic activity of antioxidant metabolism enzymes of juvenile rainbow trout with short term (6, 12, 24, 48 and 96. h) and long term (21 days) exposures followed by a recovery treatment. This study also aims to determine the effects of glyphosate exposure on liver tissue damage and swimming performance due to short term (2.5, 5 and 10. mg/L) and long term (2.5 and 5. mg/L) exposures. Following pesticide administration, ten fish, each as a sample, were caught at 6th, 12th, 24th, 48th and 96th -hfor the short term, and at 21st day for the long term exposure study. GP. x activity was found to be significantly induced 12. hafter the exposure to 2.5. mg/L of glyphosate as compared with the control group. A similar degree of induction was also observed for CAT activity but not for SOD. For long term exposure, except for the GP. x activity after exposure to 5. mg/L of glyphosate, the activities of all other enzymes remained on a par with the control group. It was also observed that the levels of gene expression of these enzymes were not comparable with each other. It is assumed that these differences might result from the effect of glyphosate before translation and the possible reasons for this scenario are also discussed. The results of swimming performance are found to be consistent with responses of the antioxidant system, and they are attributed to the energy metabolism. The data are also supported with liver histopathology analysis.
Yazarlar (11)
1
Ahmet Topal
2
Muhammed Atamanalp
3
Arzu Uçar
4
Ertan Oruç
5
Esat Mahmut Kocaman
6
Ekrem Sulukan
7
Fatih Akdemir
8
Şükrü Beydemir
9
Namik Kilinç
10
Orhan Erdoğan
11
Saltuk Buʇrahan Ceyhun
Anahtar Kelimeler
Antioxidant enzymes
Behaviour
Gene expression
Histopathology
Kurumlar
Atatürk Üniversitesi
Erzurum Turkey
Ataturk University, Faculty of Medicine
Erzurum Turkey
Metrikler
62
Atıf
11
Yazar
4
Anahtar Kelime