Scopus
YÖKSİS Eşleşti
Natural two Taraxacum species effective against frameshift and base pair substitution mutations: Mutagenic, antimutagenic and antioxidant evaluation
Marmara Pharmaceutical Journal · Ocak 2016
YÖKSİS Kayıtları
Çerçeve kayması ve baz çifti değişimi mutasyonlarına karşı etkili doğal iki Taraxacum türü Mutajenik antimutajenik antioksidan değerlendirme
Marmara Pharmaceutical Journal · 2016 ESCI
PROFESÖR AHMET UYSAL →
Natural two Taraxacum species effective against frame shift and base pair substitution mutations mutagenic antimutagenic and antioxidant evaluation
MARMARA PHARMACEUTCAL JOURNAL · 2016 ESCI
DOKTOR ÖĞRETİM ÜYESİ ERDOĞAN GÜNEŞ →
Makale Bilgileri
DergiMarmara Pharmaceutical Journal
Yayın TarihiOcak 2016
Cilt / Sayfa20 · 311-319
Scopus ID2-s2.0-84988579223
Özet
Plant or plant products have gained increasing importance in pharmacology and food industries in recent years due to their lower toxicity and side effects. The genus Taraxacum belonging to Asteraceae family have been used in traditional medicine since ancient times. In this study, antioxidant, mutagenic and antimutagenic properties of two Taraxacum species namely T. mirabile and T. farinosum were investigated. Antioxidant properties were determined by different test systems including DPPH radical scavenging, reducing power (CUPRAC and FRAP assays) and phosphomolybdenum assays. Total phenolic and flavonoid contents were also reported. Mutagenic and anti-mutagenic activities were tested by Ames assay. It was seen that Taraxacum species have moderate antioxidant and antimutagenic activities ranging between moderate to strong. However, the species were found to be non-mutagenic. It was determined that total phenolic and flavonoid contents in T. mirabile (23.43 mgGAE/g extract and 4.58 mgRE/g extract) were higher than T. farinosum (17.54 mgGAE/g extract and 3.37 mgRE/g extract).
Yazarlar (4)
1
Ahmet Uysal
2
Gokhan Zengin
ORCID: 0000-0001-6548-7823
3
Erdogan Gunes
4
Nazife Eksinar Uysal
Anahtar Kelimeler
Antimutagenic
Pharmaceuticals
Taraxacum farinosum
Taraxacum mirabile
Kurumlar
Selçuk Üniversitesi
Selçuklu Turkey
Metrikler
2
Atıf
4
Yazar
4
Anahtar Kelime