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Biological and chemical insights of Morina persica L.: A source of bioactive compounds with multifunctional properties

Journal of Functional Foods · Ağustos 2016

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YÖKSİS Kayıtları
Biological and chemical insights of Morina persica L A source of bioactive compounds with multifunctional properties
Journal of Functional Foods · 2016 SCI-Expanded
PROFESÖR ABDURRAHMAN AKTÜMSEK →
Biological and chemical insights of Morina persica L A source of bioactive compounds with multifunctional properties
Journal of Functional Foods · 2016 SCI-Expanded
PROFESÖR AHMET UYSAL →
Biological and chemical insights of Morina persica L A source of bioactive compounds with multifunctional properties
Journal of Functional Foods · 2016 SCI-Expanded
DOKTOR ÖĞRETİM ÜYESİ ERDOĞAN GÜNEŞ →

Makale Bilgileri

DergiJournal of Functional Foods
Yayın TarihiAğustos 2016
Cilt / Sayfa25 · 94-109
Özet Morina persica L. has weak rosy smell flowers that together with aerial parts are infused or decocted and used as a functional tea. It is a representative of the Anatolian traditional medicine and is used for the treatment of cold. Biological and chemical fingerprints of different extracts (methanolic, acetone and water) of M. persica were investigated. Antioxidant, enzyme inhibitory, antimicrobial, cytotoxic and mutagenic/antimutagenic effects were evaluated for biological profiling. Rutin, chlorogenic and rosmarinic acids were detected as dominant compounds. Generally, the methanolic and acetone extracts had strong antioxidant, enzyme inhibitory, antimicrobial and antimutagenic effects. Additionally, all extracts showed remarkable inhibitory effects on HeLa cells at 100 μg/mL. Furthermore, possible interactions between rutin, the dominant phenolic compound in M. persica and the tested enzymes were assessed by molecular docking. Results indicate that M. persica could be considered as a natural source of high-valued functional ingredients for further use in healthful formulations.

Yazarlar (8)

1
Andrei Mocan
2
Gokhan Zengin
ORCID: 0000-0001-6548-7823
3
Ahmet Uysal
4
Erdogan Gunes
5
Adriano Mollica
6
Nurdan Sena Degirmenci
7
Lokman Alpsoy
8
Abdurrahman Aktumsek

Anahtar Kelimeler

Cytotoxic Functional ingredients Morina persica Natural agents Rutin

Kurumlar

Fatih Üniversitesi
Istanbul Turkey
Selçuk Üniversitesi
Selçuklu Turkey
Universitatea de Medicina si Farmacie Iuliu Hatieganu din Cluj-Napoca
Cluj Napoca Romania
University of G. d'Annunzio Chieti and Pescara
Chieti Italy

Metrikler

69
Atıf
8
Yazar
5
Anahtar Kelime

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