Scopus
YÖKSİS Eşleşti
UHPLC-LTQ OrbiTrap MS analysis and biological properties of Origanum vulgare subsp. viridulum obtained by different extraction methods
Industrial Crops and Products · Ekim 2020
YÖKSİS Kayıtları
UHPLC-LTQ OrbiTrap MS analysis and biological properties of Origanum vulgare subsp. viridulum obtained by different extraction methods
Industrial Crops and Products · 2020 SCI-Expanded
PROFESÖR AHMET UYSAL →
UHPLC-LTQ OrbiTrap MS analysis and biological properties of Origanum vulgare subsp. viridulum obtained by different extraction methods
Industrial Crops and Products · 2020 SCI-Expanded
PROFESÖR GÖKHAN ZENGİN →
Makale Bilgileri
DergiIndustrial Crops and Products
Yayın TarihiEkim 2020
Cilt / Sayfa154
Scopus ID2-s2.0-85087494312
Özet
The growing awareness on implications related to the use of harsh chemicals and non-sustainable extraction methods of bioactive compounds from plants is causing a paradigm shift towards a more eco-friendly approach. The present study sets out to investigate the possible variation in the antioxidant, mutagenic/antimutagenic, antimicrobial, and enzyme inhibitory properties of Origanum vulgare subsp. viridulum extracts obtained using conventional, namely, maceration and Soxhlet extraction, and non-conventional, namely, ultrasound-assisted (UAE), microwave-assisted (MAE), and accelerated solvent extraction (ASE), techniques. Also, chemical characterization of these extracts were performed via ultrahigh-performance liquid chromatography and mass spectrometry (UHPLC-LTQ OrbiTrap MS) technique. A total of 58 polyphenols were identified in the tested extracts. Highest phenolic content was obtained from ASE (186.63 mg gallic acid equivalent [GAE]/g) and MAE (170.90 mg GAE/g) extracts. Maceration extract (18.89 mg rutin equivalent [RE]/g) showed highest flavonoid content. ASE extract showed highest activity in the DPPH (359.45 mg Trolox equivalent [TE]/g), ABTS (679.63 mg TE/g), FRAP (1433.94 mg TE/g), and CUPRAC (1685.72 mg TE/g) assays. In terms of enzyme inhibition, the UAE extract showed highest activity against acetyl cholinesterase (4.55 mg galantamine equivalent [GALAE]/g), butyryl cholinesterase (6.12 mg GALAE/g), and tyrosinase (173.87 mg kojic acid equivalent [KAE]/g) compared with the other extracts. The extracts exhibited significant antimutagenic and antimicrobial properties. Data collected from this study support the use of ASE and UAE in the extraction of bioactive compounds from Origanum vulgare subsp. viridulum aerial parts.
Yazarlar (11)
1
Gokhan Zengin
ORCID: 0000-0001-6548-7823
2
Aleksandra Cvetanović Kljakić
3
Uroš Gašić
4
Milan Dragićević
5
Alena Stupar
6
Ahmet Uysal
7
Ismail Senkardes
8
Kouadio Ibrahime Sinan
9
Carene Marie Nancy Picot-Allain
10
Gunes Ak
11
Mohamad Fawzi Mahomoodally
Anahtar Kelimeler
Antimicrobial
Chemical profile
Extraction
Mutagenity
Origanum
Kurumlar
Duy Tan University
Da Nang Viet Nam
Institute of Food Technology in Novi Sad
Novi Sad Serbia
Marmara Üniversitesi
Istanbul Turkey
Selçuk Üniversitesi
Selçuklu Turkey
University of Belgrade
Belgrade Serbia
University of Mauritius
Reduit Mauritius
University of Novi Sad
Novi Sad Serbia
Metrikler
25
Atıf
11
Yazar
5
Anahtar Kelime