Scopus
YÖKSİS DOI Eşleşti
SJR Q1
Ortho-hydroxy bioactive schiff base compounds: Design, comprehensive characterization, photophysical properties and elucidation of antimicrobial and mutagenic potentials
Bioorganic Chemistry · Şubat 2022
YÖKSİS Kayıtları
Orto-hydroxy bioactive schiff base compounds: Design, comprehensive characterization, photophysical properties and elucidation of antimicrobial and mutagenic potentials
Bioorganic Chemistry · 2022 SCI-Expanded
Prof. Dr. AHMET UYSAL →
Ortho-hydroxy bioactive schiff base compounds: Design, comprehensive characterization, photophysical properties and elucidation of antimicrobial and mutagenic potentials
Bioorganic Chemistry · 2022 SCI-Expanded
Dr. Öğr. Üyesi MUSTAFA KUL →
Ortho-hydroxy bioactive schiff base compounds: Design, comprehensive characterization, photophysical properties and elucidation of antimicrobial and mutagenic potentials
Elsevier BV · 2022 SCI-Expanded
Doç. Dr. ASLIHAN YILMAZ OBALI →
YÖKSİS Kayıtları — ISSN Eşleşmesi
Improvement of catalytic activity of Candida rugosa lipase in the presence of calix 4 arene bearing iminodicarboxylic phosphonic acid complexes modified iron oxide nanoparticles
2016 ISSN: 00452068 SCI-Expanded
Prof. Dr. ELİF ÖZYILMAZ →
Improvement of catalytic activity of Candida rugosa lipase in the presence of calix 4 arene bearing iminodicarboxylic phosphonic acid complexes modified iron oxide nanoparticles
2016 ISSN: 00452068 SCI
Prof. Dr. MUSTAFA YILMAZ →
Synthesis and evaluation of the antitumor activity of Calix [4] arene l-proline derivatives
2020 ISSN: 0045-2068 SCI
Prof. Dr. MUSTAFA YILMAZ →
Investigation of Inhibitory Properties of Some Hydrazone Compounds on hCA I, hCA II and AChE Enzymes
2019 ISSN: 0045-2068 SCI-Expanded
Prof. Dr. KAAN KÜÇÜKOĞLU →
Antibacterial activities and DNA-cleavage properties of novel fluorescent imidazo-phenanthroline derivatives
2020 ISSN: 0045-2068 SCI-Expanded
Prof. Dr. EMİNE ARSLAN →
Chemistry, structure, and biological roles of Au-NHC complexes as TrxR inhibitors
2020 ISSN: 0045-2068 SCI-Expanded
Dr. Öğr. Üyesi MERVE GÖKŞİN KARAASLAN TUNÇ →
Synthesis and evaluation of the antitumor activity of Calix[4]arene l-proline derivatives
2020 ISSN: 0045-2068 SCI-Expanded Q1
Prof. Dr. MUSTAFA YILMAZ →
Synthesis and evaluation of the antitumor activity of Calix[4]arene l-proline derivatives
2020 ISSN: 0045-2068 SCI-Expanded Q1
Doç. Dr. MEHMET OĞUZ →
New indole-7-aldehyde derivatives as melatonin analogues; synthesis and screening their antioxidant and anticancer potential
2020 ISSN: 0045-2068 SCI-Expanded
Doç. Dr. HANİF ŞİRİNZADE →
Discovery of 5-(or 6)-benzoxazoles and oxazolo[4,5-b]pyridines as novel candidate antitumor agents targeting hTopo IIα
2021 ISSN: 0045-2068 SCI-Expanded Q1
Dr. Öğr. Üyesi FATMA ZİLİFDAR FOTO →
Ortho-hydroxy bioactive schiff base compounds: Design, comprehensive characterization, photophysical properties and elucidation of antimicrobial and mutagenic potentials
2022 ISSN: 0045-2068 SCI-Expanded Q1
Dr. Öğr. Üyesi MUSTAFA KUL →
Biological activity and ADME/Tox prediction of some 2-substituted benzoxazole derivatives
2022 ISSN: 0045-2068 SCI Q1
Dr. Öğr. Üyesi FATMA ZİLİFDAR FOTO →
Ortho-hydroxy bioactive schiff base compounds: Design, comprehensive characterization, photophysical properties and elucidation of antimicrobial and mutagenic potentials
2022 ISSN: 0045-2068 SCI-Expanded
Doç. Dr. ASLIHAN YILMAZ OBALI →
Isatin-modified Calixarene derivatives: A comprehensive study on synthesis, enzyme inhibition, antioxidant, antimicrobial, and Antiproliferative activities
2025 ISSN: 0045-2068 SCI-Expanded Q1
Prof. Dr. AHMET UYSAL →
Isatin-modified Calixarene derivatives: A comprehensive study on synthesis, enzyme inhibition, antioxidant, antimicrobial, and Antiproliferative activities
2025 ISSN: 0045-2068 SCI-Expanded
Prof. Dr. MUSTAFA YILMAZ →
Preparation of water-soluble imidazole-functionalized pillar[5]arenes: The activities of antibacterial and antioxidant, catalytic reduction of 4-nitrophenol
2025 ISSN: 0045-2068 SCI-Expanded Q1
Prof. Dr. MUSTAFA ÖZMEN →
Investigation of 2-substituted-5-methylsulfonylbenzoxazole derivatives as potential cholinesterase inhibitors: Synthesis, in vitro, and computational studies
2025 ISSN: 0045-2068 SCI-Expanded Q1
Dr. Öğr. Üyesi NAGİHAN FAYDALI →
Creative approaches for antibacterial, antioxidant and anticancer using honeycomb-type agents derived from a natural polymer
2025 ISSN: 0045-2068 SCI-Expanded Q1
Prof. Dr. AHMED NURİ KURŞUNLU →
Isatin-modified Calixarene derivatives: A comprehensive study on synthesis, enzyme inhibition, antioxidant, antimicrobial, and Antiproliferative activities
2025 ISSN: 0045-2068 SCI-Expanded Q1
Doç. Dr. MEHMET OĞUZ →
Makale Bilgileri
Dergi
Bioorganic Chemistry
ISSN00452068
Yayın TarihiŞubat 2022
Cilt / Sayfa119
Scopus ID2-s2.0-85119922249
Özet
Preparation and comprehensive characterization of three Schiff base ligands; with trimethoxy substitution (1E,1′E)-N,N'-(naphthalene-1,5-diyl)bis(1-(3,4,5-trimethoxyphenyl)methanimine, 1, with ortho-hydroxy substitution 6,6′-((1E,1′E)-(naphthalene-1,5-diylbis(azaneylylidene))bis(methaneylylidene))bis(2-methoxyphenol), 2 and 3,4-bis(((E)-2-hydroxy-3-methoxy benzylidene)amino)benzoicacid, 3 and their Ni(II), Cu(II), Co(II), Zn(II), Fe(II), Mn(II) complexes have been reported. Their spectral properties were studied in solution and solid-state by a combination of different analytical techniques; FT-IR spectroscopy, 1H NMR and 13C NMR spectroscopy, elemental analysis and thermal analysis. Diamagnetic and paramagnetic natures of the complexes were also determined by magnetic susceptibility measurements in solid-state. Promising photophysical properties were observed as; Amax. were recorded at 226 nm for 2; at 795 nm for 2-Ni, at 782 nm for 2-Cu, at 784 nm for 2-Co, at 702 nm for 2-Zn, at 784 nm for 2-Fe, at 702 nm for 2-Mn and at 289 nm for 3, at 786 nm for 3-Ni, at 797 nm for 3-Cu, at 746 nm for 3-Co, at 794 nm for 3-Zn, at 699 nm for 3-Fe, at 781 nm for 3-Mn; and Imax were also recorded at; 380, 490, 725 nm for 2 and 2-Metal; 375 nm, 510 nm, 725 nm for 3 and 3-Metal when excitated at 220 nm. Antibacterial activities against different microorganisms; Escherichia coli ATCC 25922, Pseudomonas aeruginosa ATCC 27853, Klebsiella pneumoniae ATCC 70603, Staphylococcus aureus ATCC 43,300 (MRSA), Salmonella enteritidis ATTC 13076, Sarcina lutea ATCC 9341, Bacillus cereus ATTC 11778, and antifungal activities against Candida albicans NRRL Y-417 of the compounds 1, 2, 3, 2-Cu, 2-Fe, 3-Zn, 3-Fe were determined. Mutagenic properties of the compounds were also studied and according to the results 2-Cu and 3 have been found non-mutagenic in Ames test but also they have strong antimicrobial potential against pathogen microorganisms. For 2-Cu MIC values were ranging between 0.39 and 0.024 mg/ml and the lowest minimum inhibitory concentration (0.024 mg/ml) was determined against E. coli. The 3 numbered compound revealed strong antimicrobial activity at doses of ranging between 0.39 and 0.097 mg/ml and E. coli was the most sensitive bacterium against this chemical.
Yazarlar (6)
1
Israa Nıbras Qader Qader
2
I. Obali
3
Halil İsmet Uçan
4
Ahmet Uysal
5
Aslihan Yilmaz Obali
6
M. Kul
Anahtar Kelimeler
Ames test
Azomethine bond
Broth micro dilution
Mutagenicity
Naphthalene
Saloph derivatives
Kurumlar
Selçuk Üniversitesi
Selçuklu Turkey
Scimago Dergi (ISSN Eşleşmesi)
Bioorganic Chemistry
Q1
SJR Skoru0,786
H-Index95
YayıncıAcademic Press Inc.
ÜlkeUnited States
Organic Chemistry (Q1)
Biochemistry (Q2)
Drug Discovery (Q2)
Molecular Biology (Q3)
Metrikler
21
Atıf
6
Yazar
6
Anahtar Kelime