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Acetylcholinesterase inhibitory and antioxidant properties of Cyclotrichium niveum, Thymus praecox subsp. caucasicus var. caucasicus, Echinacea purpurea and E. pallida

Food and Chemical Toxicology · Haziran 2009

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YÖKSİS Kayıtları
Acetylcholinesterase inhibitory and antioxidant properties of Cyclotrichium niveum Thymus praecox subsp caucasicus var caucasicus Echinacea purpurea and E pallida
FOOD AND CHEMICAL TOXICOLOGY · 2009 SCI
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Makale Bilgileri

DergiFood and Chemical Toxicology
Yayın TarihiHaziran 2009
Cilt / Sayfa47 · 1304-1310
Özet The dichloromethane, ethyl acetate, ethanol, and aqueous extracts of Cyclotrichium niveum (CN) and Thymus praecox subsp. caucasicus var. caucasicus (TP), Echinacea purpurea (EPU), and E. pallida (EPA) along with the essential oils of CN and TP were assessed for their anti-acetylcholinesterase (AChE) and antioxidant activities. AChE inhibition was estimated using spectrophotometric method of Ellman. Antioxidant activity was evaluated by 2,2-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging and ferrous ion-chelating power tests. Ferric-reducing antioxidant power (FRAP) of CN and TP were also tested. CN essential oil was found to contain isomenthone (56.21%) and pulegone (19.76%). The ethyl acetate (83.11-87.98%) and dichloromethane (73.45-84.02%) extracts of CN showed the highest AChE inhibition. The ethyl acetate and ethanol extracts of TP exerted significant DPPH scavenger effect. The water extracts of CN and TP and the chloroform extract of the aerial parts of EPU displayed the highest ferrous ion-chelating effect. The leaf and flower essential oils of TP had the best FRAP. © 2009 Elsevier Ltd. All rights reserved.

Yazarlar (8)

1
Ilkay Erdogan Orhan
2
F. Sezer Senol
3
Ali Rifat Gulpinar
4
Murat Kartal
5
N. Şekeroglu
6
M. Deveci
7
Yüksel Kan
8
Bilge Şener

Anahtar Kelimeler

Acetylcholinesterase inhibition Antioxidant activity Cyclotrichium niveum Echinacea Essential oil Thymus praecox subsp. caucasicus var. caucasicus

Kurumlar

Ankara Üniversitesi
Ankara Turkey
Gazi Üniversitesi
Ankara Turkey
Kilis 7 Aralik Üniversitesi
Kilis Turkey
Ordu Üniversitesi
Ordu Turkey
Selçuk Üniversitesi
Selçuklu Turkey

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78
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8
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6
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