Scopus
YÖKSİS Eşleşti
Inhibitory Effects of Various Essential Oils and Individual Components against Extended-Spectrum Beta-Lactamase (ESBL) Produced by Klebsiella pneumoniae and Their Chemical Compositions
Journal of Food Science · Ekim 2011
YÖKSİS Kayıtları
Inhibitory Effects of Various Essential Oils and Individual Components against Extended-Spectrum Beta-Lactamase (ESBL) Produced by Klebsiella pneumoniae and Their Chemical Compositions
JOURNAL OF FOOD SCIENCE · 2011 SCI
PROFESÖR YÜKSEL KAN →
Inhibitory Effects of Various Essential Oils and Individual Components against Extended-Spectrum Beta-Lactamase (ESBL) Produced by Klebsiella pneumoniae and Their Chemical Compositions
JOURNAL OF FOOD SCIENCE · 2011 SCI-Expanded
PROFESÖR YÜKSEL KAN →
Makale Bilgileri
DergiJournal of Food Science
Yayın TarihiEkim 2011
Cilt / Sayfa76
Scopus ID2-s2.0-80054757001
Özet
In the current study, in vitro inhibitory activity of several essential oils obtained from the cultivated plants, Foeniculum vulgare, Mentha piperita and M. spicata, Ocimum basilicum, Origanum majorana, O. onites, O. vulgare, Satureja cuneifolia, and a number of individual essential oil components of terpene and aromatic types were screened against 10 isolated strains of Klebsiella pneumoniae producing extended-spectrum beta-lactamase (ESBL) enzyme, which makes this microorganism quite resistant against the antibiotics: trimetoprime-sulfametoksazol, sulbactam-ampicilin, clavulonate-amoxicilin, ceftriaxon, cefepime, imipenem, ceftazidime, tobramicine, gentamisine, ofloxacin, and ciprofloksasin. All of the essential oils and the components exerted a remarkable inhibition ranging between 32 and 64 μg/mL against all of these strains as strong as the references (ampicilin and oflaxocin) inhibiting at 32 μg/mL. Besides, chemical compositions of the essential oils were elucidated by gas chromatography-mass spectrometry (GC-MS). The essential oils and the pure components widely found in essential oils screened herein have shown remarkable inhibition against ESBL-producing K. pneumoniae strains, which leads to the suggestion that they may be used as food preservatives for this purpose. Practical Application: The essential oils obtained from Foeniculum vulgare, Mentha piperita and M. spicata, O.cimum basilicum, Origanum majorana, O. onites, O. vulgare, and Satureja cuneifolia as well as common essential oil components have shown notable inhibitory effects against 10 isolated strains of Klebsiella pneumoniae producing extended-spectrum beta-lactamase (ESBL) enzyme and they might be used as food preservative or ingredient. © 2011 Institute of Food Technologists ®.
Yazarlar (4)
1
Ilkay Erdogan Orhan
2
Berrin Özçelik
3
Yüksel Kan
4
Murat Kartal
Anahtar Kelimeler
Aromatic plants
ESBL
Essential oil
GC-MS
Klebsiella pneumoniae
Kurumlar
Ankara Üniversitesi
Ankara Turkey
Eastern Mediterranean University
Famagusta Turkey
Gazi Üniversitesi
Ankara Turkey
Selçuk Üniversitesi
Selçuklu Turkey
Metrikler
42
Atıf
4
Yazar
5
Anahtar Kelime