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Immunomodulatory properties of various natural compounds and essential oils through modulation of human cellular immune response

Industrial Crops and Products · Mart 2016

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YÖKSİS Kayıtları
Immunomodulatory properties of various natural compounds and essential oils through modulation of human cellular immune response
INDUSTRIAL CROPS AND PRODUCTS · 2016 SCI
Prof. Dr. YÜKSEL KAN →
Immunomodulatory properties of various natural compounds and essential oils through modulation of human cellular immune response
Industrial Crops and Products · 2016 SCI
Prof. Dr. YÜKSEL KAN →
YÖKSİS ISSN Eşleşmesi

Bu dergide (ISSN eşleşmesi) kurumun 20 kaydı bulundu.

YÖKSİS Kayıtları — ISSN Eşleşmesi
A comprehensive study on phytochemical characterization of Haplophyllum myrtifolium Boiss endemic to Turkey and its inhibitory potential against key enzymes involved in Alzheimer skin diseases and type II diabetes
2014 ISSN: 09266690 SCI-Expanded 4 atıf
Prof. Dr. GÖKHAN ZENGİN →
HPLC DAD analysis of phenolic compounds and antioxidant properties of Asphodeline lutea roots from Bulgaria and Turkey
2014 ISSN: 09266690 SCI-Expanded 1 atıf
Prof. Dr. GÖKHAN ZENGİN →
Phenolic constituent antioxidative and tyrosinase inhibitory activity of Ornithogalum narbonense L from Turkey A phytochemical study
2015 ISSN: 09266690 SCI-Expanded 1 atıf
Prof. Dr. GÖKHAN ZENGİN →
Composition antioxidant antimicrobial and enzyme inhibition activities of two Origanum vulgare subspecies subsp vulgare and subsp hirtum essential oils
2015 ISSN: 09266690 SCI-Expanded
Prof. Dr. GÖKHAN ZENGİN →
Changes in the fatty acid compositions and bioactivities of clary sage seeds depending on harvest year
2012 ISSN: 0926-6690 SCI-Expanded
Prof. Dr. ERAY TULUKCU →
A phytochemical study on Potentilla anatolica An endemic Turkish plant
2015 ISSN: 09266690 SCI-Expanded
Prof. Dr. ABDURRAHMAN AKTÜMSEK →
Phenolic constituent antioxidative and tyrosinase inhibitory activity of Ornithogalum narbonense L from Turkey A phytochemical study
2015 ISSN: 09266690 SCI-Expanded
Prof. Dr. ABDURRAHMAN AKTÜMSEK →
Composition antioxidant antimicrobial and enzyme inhibition activities of two Origanum vulgare subspecies subsp vulgare and subsp hirtum essential oils
2015 ISSN: 09266690 SCI-Expanded
Prof. Dr. ABDURRAHMAN AKTÜMSEK →
HPLC DAD analysis of phenolic compounds and antioxidant properties of Asphodeline lutea roots from Bulgaria and Turkey
2014 ISSN: 09266690 SCI-Expanded
Prof. Dr. ABDURRAHMAN AKTÜMSEK →
A comprehensive study on phytochemical characterization of Haplophyllum myrtifolium Boiss endemic to Turkey and its inhibitory potential against key enzymes involved in Alzheimer skin diseases and type II diabetes
2014 ISSN: 09266690 SCI-Expanded
Prof. Dr. ABDURRAHMAN AKTÜMSEK →
Chemical and biological fingerprints of two Fabaceae species Cytisopsis dorycniifolia and Ebenus hirsuta Are they novel sources of natural agents for pharmaceutical and food formulations
2016 ISSN: 09266690 SCI-Expanded
Prof. Dr. ABDURRAHMAN AKTÜMSEK →
A study on in vitro enzyme inhibitory properties of Asphodeline anatolica New sources of natural inhibitors for public health problems
2016 ISSN: 09266690 SCI-Expanded
Prof. Dr. GÖKHAN ZENGİN →
Immunomodulatory properties of various natural compounds and essential oils through modulation of human cellular immune response
2016 ISSN: 09266690 SCI
Prof. Dr. YÜKSEL KAN →
Enzyme inhibitory and antioxidant activities of Nerium oleander L. flower extracts and activity guided isolation of the active components
2018 ISSN: 09266690 SCI-Expanded
Prof. Dr. GÖKHAN ZENGİN →
HPLC–MS/MS-based metabolic profiling and pharmacological properties of extracts and infusion obtained from Amelanchier parviflora var. dentata
2018 ISSN: 0926-6690 SCI-Expanded
Prof. Dr. GÖKHAN ZENGİN →
Enzyme inhibitory and antioxidant activities of Nerium oleander L. flower extracts and activity guided isolation of the active components
2018 ISSN: 0926-6690 SCI-Expanded Q1
Prof. Dr. GÖKHAN ZENGİN →
Bioactivity-guided isolation of cytotoxic secondary metabolites from the roots of Glycyrrhiza glabra and elucidation of their mechanisms of action
2018 ISSN: 0926-6690 SCI-Expanded
Prof. Dr. YÜKSEL KAN →
Lotus aegaeus (Gris.) Boiss and Iberis sempervirens L.: Chemical fingerprints, antioxidant potential, and inhibition activities and docking on key enzymes linked to global health problems
2018 ISSN: 0926-6690 SCI-Expanded
Prof. Dr. ABDURRAHMAN AKTÜMSEK →
Exploring the therapeutic potential and phenolic composition of two Turkish ethnomedicinal plants – Ajuga orientalis L. and Arnebia densiflora (Nordm.) Ledeb.
2018 ISSN: 0926-6690 SCI-Expanded
Prof. Dr. ABDURRAHMAN AKTÜMSEK →
Insight into the biological properties and phytochemical composition of Ballota macrodonta Boiss. et Balansa, — an endemic medicinal plant from Turkey
2018 ISSN: 0926-6690 SCI-Expanded
Prof. Dr. GÖKHAN ZENGİN →

Makale Bilgileri

Dergi Industrial Crops and Products
ISSN09266690
Yayın TarihiMart 2016
Cilt / Sayfa81 · 117-122
DOI10.1016/j.indcrop.2015.11.088
Scopus ID2-s2.0-84949955237
Özet Randomly selected essential oils and some terpene and phenolic derivatives were evaluated for their ability to modulate human cellular immune responses using various inflammatory parameters including reactive oxygen species (ROS) generation from whole blood phagocytes and isolated polymorphonuclear neutrophils (PMNs), proliferation of T-cells, IL-2. and TNF-α cytokine production. The essential oils from Foeniculum vulgare, Saturea cuneifolia, and Origanum munitiflorum inhibited ROS produced from whole blood phagocytes, while thymol, carvacrol, rosmarinic acid, caffeic acid, quercetin, and kaempferol glycoside potently inhibited the ROS production from whole blood as well as from isolated PMNs, among which caffeic acid, quercetin, and kaempferol glycoside exhibited a better inhibitory effect than that of ibuprofen. The compounds rosmarinic acid, caffeic acid, quercetin, kaempferol glycoside, genistein, and apigenin (IC50 7.0±0.5, <3.12, <3.12, 4.3±1.0, 5.8±0.5, and <3.12μg/mL) were found to exert potent inhibition on proliferation of T-cells. On the other hand, quercetin (IC50 2.9±0.3μg/mL) and apigenin (IC50 <1.0μg/mL), were also found to be the potent inhibitor of IL-2 cytokine. The essential oils of Mentha species, and compounds quercetin and apigenin were found to potently inhibit the production of pro-inflammatory cytokine TNF-α. The results indicated that essential oils and phenolics might be considered as promising immunomodulatory agents.

Yazarlar (4)

1
Ilkay Erdogan Orhan
2
M. Ahmed Mesaik
3
Almas Jabeen
4
Yüksel Kan

Anahtar Kelimeler

Cytokine Essential oil Immunomodulatory activity Natural compound ROS T-cell proliferation TNF-α

Kurumlar

Gazi Üniversitesi
Ankara Turkey
Selçuk Üniversitesi
Selçuklu Turkey
Universiti Kebangsaan Malaysia
Bangi Malaysia
University of Karachi
Karachi Pakistan
Scimago Dergi (ISSN Eşleşmesi)
Industrial Crops and Products
Q1
SJR Skoru0,974
H-Index186
YayıncıElsevier B.V.
ÜlkeNetherlands
Agronomy and Crop Science (Q1)
Dergi sayfasına git

Metrikler

29
Atıf
4
Yazar
7
Anahtar Kelime

Sistemimizdeki Yazarlar

YK
YÜKSEL KAN
Prof. Dr.

Hızlı Erişim

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