Scopus
YÖKSİS Eşleşti
Secondary metabolites, phytochemical characterization and antioxidant activities of different extracts of Sideritis congesta P.H. Davis et Hub.-Mor.
Biochemical Systematics and Ecology · Ekim 2020
YÖKSİS Kayıtları
Secondary metabolites, phytochemical characterization and antioxidant activities of different extracts of Sideritis congesta PH Davis et Hub.-Mor.
BIOCHEMICAL SYSTEMATICS AND ECOLOGY · 2020 SCI
PROFESÖR YÜKSEL KAN →
Makale Bilgileri
DergiBiochemical Systematics and Ecology
Yayın TarihiEkim 2020
Cilt / Sayfa92
Scopus ID2-s2.0-85088946032
Özet
Sideritis congesta, an endemic plant to Turkey, is extensively consumed as energizing herbal tea and used as a remedy in folk medicine. This study was designed to comparatively evaluate the phytochemical composition and antioxidant potentials of different extracts (methanol, infusion) and fractions (chloroform, ethyl acetate, and remaining water) of S. congesta. Antioxidant potentials of the samples were evaluated by DPPH radical scavenging, FRAP, CUPRAC, and total antioxidant capacity tests. Total phenolic, phenolic acid, and flavonoid contents were also evaluated spectrophotometrically. Moreover, presence of twenty-two phenolic metabolites were affirmed by using LC-MS/MS in MRM scan mode and then the quantification of verbascoside, martynoside, and leucoseptoside A was performed by using HPTLC densitometry. EtOAc fraction contained the highest phenolic content and the antioxidant activity, as well as the highest verbascoside and martynoside contents followed by R-H2O fraction. Phytochemical studies on R-H2O fraction, yielded seven compounds, including a phenylethanoid glycoside, verbascoside (1), two flavonoids, stachyspinoside (2), isoscutellarein 7-O-(6‴-O-acetyl)-β-allopyranosyl-(1 → 2)-β-glucopyranoside (3), a phenolic acid chlorogenic acid (4), an iridoid glycoside ajugoside (5), and a monoterpenoid glucoside mixture betulalbuside A (6) and 1-hydroxylinaloyl 6-O-β-D-glucopyranoside (7). The molecular structures of the isolated compounds were determined by NMR and MS experiments. This is the first phytochemical study on the polar constituent of S. congesta and the first report of the isolation of compounds 2, 6 and 7 from the genus Sideritis L.
Yazarlar (6)
1
Hilal Bardakci
2
Dicle Çevik
ORCID: 0000-0001-9257-5765
3
Timur Hakan Barak
4
Tuba Gozet
5
Yüksel Kan
6
Hasan Kırmızıbekmez
Anahtar Kelimeler
Antioxidant activity
HPTLC
LC–MS/MS
Secondary metabolites
Sideritis congesta
Kurumlar
Acıbadem Mehmet Ali Aydınlar Üniversitesi
Istanbul Turkey
Altinbas Universitesi
Istanbul Turkey
Selçuk Üniversitesi
Selçuklu Turkey
Yeditepe University
Istanbul Turkey
Metrikler
16
Atıf
6
Yazar
5
Anahtar Kelime