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Evaluation of pathological changes in broilers during chronic aflatoxin (50 and 100 ppb) and clinoptilolite exposure

Research in Veterinary Science · Şubat 2005

Makale Bilgileri

DergiResearch in Veterinary Science
Yayın TarihiŞubat 2005
Cilt / Sayfa78 · 61-68
Özet This study was conducted to evaluate the pathological changes in broilers fed a diet containing low-levels of aflatoxin (AF) and clinoptilolite (CLI) until 42 days of age. A total of 576 one-day-old Ross-308 type broiler chicks were treated with varying levels of AF and CLI (15 g kg-1). The gross and histopathological changes in the liver, kidneys, spleen, thymus and bursa of Fabricius were investigated and relative organ weights were calculated. Compared to controls, significant changes (P < 0.05), such as slight to moderate hydropic degeneration and/or fatty change (8 cases of 10), bile-duct hyperplasia (7 of 10) and periportal fibrosis (5 of 10), were found in chicks fed 100 ppb AF-containing diet. No gross-pathological changes were observed in any treatments. The addition of CLI to the 100 ppb AF-containing diet significantly decreased the number of affected broilers and/or the severity of lesions (hydropic degeneration and bile-duct hyperplasia) in the livers (P < 0.05). The addition of CLI to the AF-free diet did not produce any significant lesions compared with the controls. © 2004 Published by Elsevier Ltd.

Yazarlar (4)

1
M. Ortatatli
2
H. Oǧuz
3
Fatih Hatipoglu
4
M. Karaman

Kurumlar

Selçuk Üniversitesi
Selçuklu Turkey

Metrikler

146
Atıf
4
Yazar

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