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The effect of testosterone used in sportsmen on routine biochemical parameters

Journal of Animal and Veterinary Advances · Ekim 2010

Makale Bilgileri

DergiJournal of Animal and Veterinary Advances
Yayın TarihiEkim 2010
Cilt / Sayfa9 · 2038-2040
Özet The purpose of the research was to determine indicators of testosterone implication on heart, liver and kidney failure in female rats during puberty and also to determine its effect on some other chemical values. In the research, female 16 Sprague dawley rats (50 days) were used. The rats were divided into two equal groups. The first group was administrated testosterone, diluted with olive oil, 5 mg kg-1 (SID) subcutaneously for 10 weeks, 5 days each week. The second group was only given olive oil. Serum creatine kinase, creatine kinase-MB, alkaline phosphates, alamne ammo trans ferase, aspartate aminotransferase, blood urea nitrogen, creatinine, triglyceride, cholesterol, high density lipoprotein, amylase, total protein, albumin and calcium were measured with an auto-analyzer. It was determined that while testosterone application in female rats leads to decrease on the total serum protein and albumin levels (p<0.05), it increased aspartate aminotransferase and cholesterol levels (p<0.05). Consequently, it can be stated that long term testosterone implication during puberty may lead to organ defects at early ages. © Medwell Journals, 2010.

Yazarlar (4)

1
Erdal Tasgin
2
Sefa Lök
3
Nagehan Demir
4
Mehmet Ozdemir

Anahtar Kelimeler

Albumin Aspartate aminotransferase Cholesterol Testosterone Total protein Turkey

Kurumlar

Selçuk Üniversitesi
Selçuklu Turkey

Metrikler

5
Atıf
4
Yazar
6
Anahtar Kelime

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