Scopus
Combined usage of testosterone and nandrolone may cause heart damage
African Journal of Biotechnology · Mayıs 2011
Makale Bilgileri
DergiAfrican Journal of Biotechnology
Yayın TarihiMayıs 2011
Cilt / Sayfa10 · 3766-3768
Scopus ID2-s2.0-79957575678
Özet
The aim of this study is to determine the effects of combined application of testosterone and nandrolone on male rabbits during adolescence period for biochemical values which are indicators of damage to heart, liver and kidney. Seven male New Zealand white rabbits, 60-days old, were used in this study. Testosterone (10 mg/kg) + nandrolone deconoate (10 mg/kg) were injected simultaneously to the rabbits in an intramuscular manner once in 1 week for a period of 12 weeks. Blood samples were taken in 0, 4, 8 and 12 weeks. Serum creatine kinase-MB, lactate dehydrogenase, alkaline phosphatase, alanine aminotransferase, aspartate aminotransferase, gamma-glutamyl-transferase, creatinine and blood urea nitrogen were measured with an auto-analyzer. Combined use of testosterone and nandrolone caused (p < 0.05) increase in serum creatine kinase-MB activity, but no statistical changes (p > 0.05) were determined in other parameters. As a result, it can be concluded that the use of testosterone plus nandrolone simultaneously during early ages may cause heart damage. © 2011 Academic Journals.
Yazarlar (3)
1
Erdal Tasgin
2
Sefa Lök
3
Nagehan Demir
Anahtar Kelimeler
Creatine kinase-MB
Nandrolone
Testosterone
Kurumlar
Selçuk Üniversitesi
Selçuklu Turkey
Metrikler
7
Atıf
3
Yazar
3
Anahtar Kelime