Scopus
YÖKSİS DOI Eşleşti
SJR Q2
Effect of Zinc and Melatonin on Oxidative Stress and Serum Inhibin-B Levels in a Rat Testicular Torsion–Detorsion Model
Biochemical Genetics · Aralık 2017
YÖKSİS Kayıtları
Effect of Zinc and Melatonin on Oxidative Stress and Serum Inhibin-B Levels in a Rat Testicular Torsion-Detorsion Model.
BIOCHEMICAL GENETICS · 2017 SCI-Expanded
Prof. Dr. ABDULKERİM KASIM BALTACI →
YÖKSİS Kayıtları — ISSN Eşleşmesi
Isolation and sequence analysis of wheat NBS LRR type disease resistance gene analogs using degenerate PCR primers
2007 ISSN: 0006-2928 SCI-Expanded
Prof. Dr. ERDOĞAN EŞREF HAKKI →
Is the IL 6 174G C Gene Polymorphism Related to the Disease Severity Score in Turkish Children with Familial Mediterranean Fever
2016 ISSN: 0006-2928 SCI-Expanded
Prof. Dr. RESUL YILMAZ →
Leptin, NPY, Melatonin and Zinc Levels in Experimental Hypothyroidism and Hyperthyroidism: The Relation to Zinc
2017 ISSN: 0006-2928 SCI-Expanded
Prof. Dr. ABDULKERİM KASIM BALTACI →
Effect of Zinc and Melatonin on Oxidative Stress and Serum Inhibin-B Levels in a Rat Testicular Torsion-Detorsion Model.
2017 ISSN: 0006-2928 SCI-Expanded
Prof. Dr. ABDULKERİM KASIM BALTACI →
Clinical and Demographic Evaluation According to MEFV Genes in Patients with Familial Mediterranean Fever
2019 ISSN: 0006-2928 SCI-Expanded
Prof. Dr. RESUL YILMAZ →
Assessment of Pathogenic Variants in the PAH Gene and Genotype–Phenotype Correlation in Phenylketonuria Patients from Turkey
2025 ISSN: 0006-2928 SCI-Expanded Q4
Dr. Öğr. Üyesi BANU KADIOĞLU YILMAZ →
Makale Bilgileri
Dergi
Biochemical Genetics
ISSN00062928
Yayın TarihiAralık 2017
Cilt / Sayfa55 · 395-409
Scopus ID2-s2.0-85032789037
Özet
The present study was aimed to examine the effects of 3-week zinc and melatonin administration on testicular tissue injury and serum Inhibin-B levels caused by unilateral testicular torsion–detorsion in rats. The study was performed on 60 Wistar Albino-type adult male rats. The animals were allocated to 6 groups in equal numbers. 1. Control; 2. Sham; 3. Ischemia–reperfusion; 4. Zinc + ischemia–reperfusion; 5. Melatonin + ischemia–reperfusion; 6. Zinc + melatonin + ischemia–reperfusion. Zinc and melatonin were administered before ischemia–reperfusion at doses of 5 and 3 mg/kg respectively, by intraperitoneal route for a period of 3 weeks. Testicular torsion–detorsion procedures consisted of ischemia for 1 h and then reperfusion for another hour of the left testis. Blood and testicular tissue samples were collected to analyze erythrocyte and tissue GSH and plasma and tissue MDA, Inhibin-B levels. The highest erythrocyte and testis GSH values were found in zinc, melatonin, and zinc + melatonin groups (p < 0.001). Torsion–detorsion group has significantly lower erythrocyte GSH levels and higher plasma MDA values (p < 0.001). Serum inhibin-B and spermatogenic activity levels in the torsion–detorsion group were also significantly lower than those in the other groups (p < 0.001). However, zinc-, melatonin-, and melatonin + zinc-supplemented groups have higher inhibin-B and spermatogenetic activity (p < 0.001). The results of the study show that zinc, melatonin, and melatonin + zinc administration partially restores the increased oxidative stress, as well as the reduced inhibin-B and spermatogenic activity levels in testes ischemia–reperfusion in rats. Suppressed inhibin-B levels in the testicular tissue may be a marker of oxidative stress.
Yazarlar (4)
1
Atilla Semercioz
2
Abdulkerim Kasim Baltaci
3
Rasim Mogulkoc
4
Mustafa Avunduk
Anahtar Kelimeler
Inhibin-B
Melatonin
Testis torsion–detorsion
Tissue injury
Zinc
Kurumlar
Bağcilar Eğitim ve Araştirma Hastanesi
Istanbul Turkey
Necmettin Erbakan Üniversitesi
Meram Turkey
Selçuk Üniversitesi
Selçuklu Turkey
Scimago Dergi (ISSN Eşleşmesi)
Biochemical Genetics
Q2
SJR Skoru0,544
H-Index50
YayıncıSpringer
ÜlkeUnited States
Ecology, Evolution, Behavior and Systematics (Q2)
Medicine (miscellaneous) (Q2)
Biochemistry (Q3)
Genetics (Q3)
Molecular Biology (Q3)
Metrikler
34
Atıf
4
Yazar
5
Anahtar Kelime