Scopus
YÖKSİS Eşleşti
The Effect of Chronic Swimming Exercise and Vitamin E Supplementation on Bone Element Metabolism in Epileptic Rats
Noropsikiyatri Arsivi · Haziran 2024
YÖKSİS Kayıtları
The Effect of Chronic Swimming Exercise and Vitamin E Supplementation on Bone Element Metabolism in Epileptic Rats
NOROPSIKIYATRI ARSIVI-ARCHIVES OF NEUROPSYCHIATRY · 2024 Art Index (Art Research Database, EBSCO)
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Makale Bilgileri
DergiNoropsikiyatri Arsivi
Yayın TarihiHaziran 2024
Cilt / Sayfa61 · 113-118
Scopus ID2-s2.0-85196398472
Özet
Introduction: This study aimed to investigate the effects of chronic swimming exercise and vitamin E administration on elemental levels in the bone tissue of epileptic rats. Methods: Forty-eight rats were divided into six groups: Control, Swimming, Swimming + vitamin E, Swimming + Epilepsy, Swimming + Epilepsy + vitamin E, and Epilepsy. Vitamin E was administered to the animals chronically by gavage at a dose of 500 mg/kg every other day for 3 months. Epileptiform activity was induced with penicillin in animals 24 hours after the last vitamin E intake. The exercise program consisted of daily 30-minute swimming sessions. At the end of the treatment period, the levels of calcium, chromium, copper, iron, magnesium, manganese, lead, and zinc (µg/gram tissue) in bone tissue samples were measured using an atomic emission device.Results: The results showed that all epileptic groups had significantly lower bone chromium levels compared to the control groups (p<0.05). The epileptic, and epileptic swimming groups had the lowest levels of bone calcium, magnesium, and zinc (p<0.05). Vitamin E administration resulted in a significant increase in bone calcium, magnesium, and zinc levels in the epileptic swimming group with vitamin E compared to the epileptic and epileptic swimming groups. (p<0.05). Conclusion: The findings of the study show that the administration of vitamin E improves calcium, magnesium, and zinc metabolism in the deteriorated bone tissue of the epileptic rat model.
Yazarlar (7)
1
Saltuk Bugra Baltaci
2
Erkut Tutkun
3
Mustafa Ayyildiz
4
Erdal Ağar
5
Gökhan Arslan
6
Rasim Mogulkoc
7
Abdulkerim Kasim Baltaci
Anahtar Kelimeler
Bone elemental metabolism
epilepsy
rat
swimming exercise
vitamin E
Kurumlar
Bursa Uludağ Üniversitesi
Bursa Turkey
İstanbul Medipol Üniversitesi
Istanbul Turkey
Ondokuz Mayis University, Medical School
Samsun Turkey
Selçuk Tip Fakültesi
Konya Turkey