Scopus
YÖKSİS Eşleşti
Cytotoxic, phytotoxic and insecticidal activities of chrysophthalmum montanum (DC.) Boiss
Turkish Journal of Pharmaceutical Sciences · Aralık 2017
YÖKSİS Kayıtları
Cytotoxic, Phytotoxic and Insecticidal Activities of Chrysophthalmum montanum (DC.) Boiss.
The Turkish Journal of Pharmaceutical Sciences · 2017 Emerging Sources Citation Index (ESCI), Scopus SJR, Embase, Ebsco
DOÇENT FATMA AYAZ →
Makale Bilgileri
DergiTurkish Journal of Pharmaceutical Sciences
Yayın TarihiAralık 2017
Cilt / Sayfa14 · 290-293
Scopus ID2-s2.0-85035038175
Özet
Objectives: To investigate the in vitro cytotoxic, phytotoxic, and insecticidal activity of Chrysophthalmum montanum (DC.) Boiss. Materials and Methods: The crude methanol (80%) extract of the aerial parts of C. montanum was fractionated to obtain n-hexane, chloroform, n-butanol, and remaining water fractions. The crude extract and subsequent solvent fractions of the plant were evaluated for their biological activities using screening bioassays such as cytotoxicity on brine shrimp lethality, phytotoxicity against Lemna minor L., and insecticidal activity against Rhyzopertha dominica and Tribolium castaneum. Results: The cytotoxicity assay revealed that the crude extract, n-hexane, and chloroform fractions of the plant had positive lethality with LD 50 values of 71.51, 126.62, and 75.95 µg/mL, respectively. The extract and its fractions, except for the remaining water fraction, showed phytotoxic activity, which was expressed as percentage growth regulation in a concentration-dependent manner. n-hexane and chloroform fractions in particular had 100% growth inhibition (GI) at 1000 µg/mL, followed by the n-butanol fraction (62.6% GI) and crude extract (40.0% GI) of the plant at the same concentration. Otherwise, all samples had no insecticidal activity against R. dominica and T. castaneum. Conclusion: This study demonstrates that C. montanum contains bioactive compounds related to potential biological activities such as cytotoxic and phytotoxic.
Yazarlar (5)
1
Fatma Ayaz
2
Nurgün Küçükboyacı
3
Hayri Duman
4
Bilge Şener
5
M. Iqbal Choudhary
Anahtar Kelimeler
Asteraceae
Chrysophthalmum montanum
Cytotoxic activity
Insecticidal activity
Phytotoxic activity
Kurumlar
Gazi Üniversitesi
Ankara Turkey
University of Karachi
Karachi Pakistan
Metrikler
8
Atıf
5
Yazar
5
Anahtar Kelime