Scopus
🔓 Açık Erişim
Phytotoxic, cytotoxic and insecticidal activities of chrysophthalmum dichotomum boiss. and Heldr.
Indian Journal of Pharmaceutical Education and Research · Temmuz 2018
Makale Bilgileri
DergiIndian Journal of Pharmaceutical Education and Research
Yayın TarihiTemmuz 2018
Cilt / Sayfa52 · 467-471
Scopus ID2-s2.0-85057238458
Erişim🔓 Açık Erişim
Özet
Background: Chrysophthalmum dichotomum Boiss. and Heldr. (Asteraceae) is an endemic herbaceous plant to Southern part of Turkey. Aim: To investigate in vitro phytotoxic, cytotoxic and insecticidal activities of C. dichotomum. Methods: The MeOH extract of C. dichotomum was fractionated through subsequent solvent extractions in increasing polarity with n-hexane, chloroform and n-butanol. The MeOH extract and its fractions were evaluated for their biological acitivities using in vitro screening bioassays such as cytotoxicity on brine shrimps, phytotoxicity against Lemna minor and insecticidal activity against Rhyzopertha dominica and Tribolium castaneum. Results: The n-hexane and chloroform fractions showed significant phytotoxic activity (100 % growth inhibition) at 1000 μg/ml against L. minor. The brine shrimp lethality test revealed that the chloroform and remaining water fractions of C. dichotomum have moderate and positive lethality with LD50 values of 169.48 and 46.26 µg/mL, respectively. In addition, the chloroform and n-butanol fractions had low and moderate insecticidal activity with 20 and 40 % of mortality against Tribolium castaneum, respectively. Conclusion: This study demonstrates that C. dichotomum consists of bioactive constituents responsible for phytotoxicity, cytotoxicity on brine shrimps and insecticidal activity.
Yazarlar (5)
1
Fatma Ayaz
2
Nurgün Küçükboyacı
3
Barış Bani
4
Bilge Şener
5
M. Iqbal Choudhary
Anahtar Kelimeler
Asteraceae
Chrysophthalmum dichotomum
Cytotoxicity on brine shrimps
Insecticidal activity
Phytotoxicity against lemna minor
Kurumlar
Gazi Üniversitesi
Ankara Turkey
Kastamonu University
Kastamonu Turkey
Selçuk Üniversitesi
Selçuklu Turkey
University of Karachi
Karachi Pakistan
Metrikler
3
Atıf
5
Yazar
5
Anahtar Kelime