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Anti-saccharomyces cerevisiae as unusual antibody in autoimmune polyglandular syndrome type III: A case report

Endocrine, Metabolic and Immune Disorders - Drug Targets · Ocak 2019

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YÖKSİS Kayıtları
Anti-Saccharomyces Cerevisiae as Unusual Antibody in Autoimmune Polyglandular Syndrome Type III: A Case Report
ENDOCRINE METABOLIC & IMMUNE DISORDERS-DRUG TARGETS · 2019 SCI-Expanded
DOKTOR ÖĞRETİM ÜYESİ AHMET GÖRGEL →

Makale Bilgileri

DergiEndocrine, Metabolic and Immune Disorders - Drug Targets
Yayın TarihiOcak 2019
Cilt / Sayfa19 · 90-94
Özet Backgraund and Objective: Anti-Saccharomyces Cerevisiae Antibodies (ASCA) that are considered to reflect immune response against increased intestinal permeability due to mucosal damage are among the serological markers of Crohn’s Disease. Methods: This microbial seromarker was recently shown to be elevated in several autoimmune disorders such as celiac disease, autoimmune liver diseases, type 1 diabetes, and Graves’ disease. Despite that fact, ASCA seropositivity in Autoimmune Polyglandular Syndrome (APS) has never been reported before. Results: Herein, we present a 46-year-old woman who has uveitis, autoimmune thyroiditis, and primary ovarian failure. Conclusion: Based on the coexistence of these diseases, the patient was diagnosed with APS type III. Moreover, ASCA seropositivity was detected although she has no overt intestinal disease.

Yazarlar (3)

1
Ahmet Gorgel
2
Cem Cankaya
3
Mehmet Tecellioglu

Anahtar Kelimeler

Anti-double-stranded DNA Antinuclear antibody Anti-Saccharomyces Cerevisiae Antibody (ASCA) Autoimmune hepatititis Autoimmune Polyglandular Syndrome (APS) type III Uveitis

Kurumlar

Private Malatya Gozde Hospital
Malatya Turkey