Scopus
🔓 Açık Erişim YÖKSİS DOI Eşleşti
SJR Q3
Plasma disposition of cefoperazone after single intravenous and intramuscular administrations in camels (Camelus dromedarius)
Acta Veterinaria Hungarica · Eylül 2018
YÖKSİS Kayıtları
Plasma disposition of cefoperazone after single intravenous and intramuscular administrations in camels (Camelus dromedarius) )/title
Acta Veterinaria Hungarica · 2018 SCI-Expanded
Prof. Dr. MUAMMER ELMAS →
title Plasma disposition of cefoperazone after single intravenous and intramuscular administrations in camels ( iCamelus dromedarius/i )/title
Acta Veterinaria Hungarica · 2018 SCI-Expanded
Prof. Dr. KAMİL ÜNEY →
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Plasma disposition of cefoperazone after single intravenous and intramuscular administrations in camels (Camelus dromedarius) )/title
2018 ISSN: 0236-6290 SCI-Expanded
Prof. Dr. MUAMMER ELMAS →
title Plasma disposition of cefoperazone after single intravenous and intramuscular administrations in camels ( iCamelus dromedarius/i )/title
2018 ISSN: 0236-6290 SCI-Expanded
Prof. Dr. KAMİL ÜNEY →
Assessment of the cardiotoxicity of tulathromycin in rabbits
2011 ISSN: 0236-6290 SSCI
Prof. Dr. ENVER YAZAR →
Effect of pentoxifylline on endotoxin-induced haemostatic, disturbances in rabbits
2005 ISSN: 0236-6290 SCI-Expanded
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Changes In Novel Gastrointestinal And Renal Injury Markers In The Blood Plasma Of Sheep Following Increasing Intravenous Doses Of Tolfenamic Acid
2019 ISSN: 0236-6290 SCI
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Heart-type fatty acid-binding protein (H-FABP), pentraxin-3 (PTX-3) and thrombomodulin in bovine traumatic pericarditis
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CHANGES IN NOVEL GASTROINTESTINAL AND RENAL INJURY MARKERS IN THE BLOOD PLASMA OF SHEEP FOLLOWING INCREASING INTRAVENOUS DOSES OF TOLFENAMIC ACID
2019 ISSN: 0236-6290 SCI
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2012 ISSN: 0236-6290 SCI-Expanded
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Makale Bilgileri
ISSN02366290
Yayın TarihiEylül 2018
Cilt / Sayfa66 · 444-450
Scopus ID2-s2.0-85055126117
Erişim🔓 Açık Erişim
Özet
The plasma disposition of cefoperazone was investigated after intravenous (IV) and intramuscular (IM) administrations of 20 mg/kg as a single dose in six camels (Camelus dromedarius) in a crossover design. Blood plasma samples were analysed by high-performance liquid chromatography (HPLC). After IV administration, elimination half-life (t 1/2β ), volume of distribution at steady state (V dss ), total body clearance (Cl tot ) and mean residence time (MRT) of cefoperazone were 1.95 h, 0.38 L/kg, 0.17 L/h/kg and 2.16 h, respectively. After IM administration of cefoperazone, peak plasma concentration (C max ) was 21.95 μg/mL and it was obtained at (t max ) 1.23 h. Absorption half-life (t 1/2ab ), elimination half-life and mean absorption time were 0.45 h, 2.84 h and 2.07 h, respectively. The bioavailability of cefoperazone was 89.42%. The lack of local reaction or any other adverse effects and the very good bioavailability following IM administration indicate that cefoperazone might be a promising alternative treatment for a variety of infectious diseases in camels.
Yazarlar (4)
1
Mohamed Aboubakr
2
Ahmed Soliman
3
Kamil Üney
ORCID: 0000-0002-8674-4873
4
M. Elmas
Anahtar Kelimeler
Bioavailability
Camels
Cefoperazone
Concentrations
Kurumlar
Faculty of Veterinary Medicine
Giza Egypt
Faculty of Veterinary Medicine Benha University
Benha Egypt
Selçuk Üniversitesi
Selçuklu Turkey
Scimago Dergi (ISSN Eşleşmesi)
Acta Veterinaria Hungarica
Q3
SJR Skoru0,281
H-Index42
YayıncıAkademiai Kiado ZRt.
ÜlkeHungary
Veterinary (miscellaneous) (Q3)