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Scopus YÖKSİS DOI Eşleşti SJR Q2

The embryotoxic and teratogenic effects of metamizole sodium

Journal of Veterinary Medicine Series C Anatomia Histologia Embryologia · Eylül 2024

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YÖKSİS Kayıtları
The embryotoxic and teratogenic effects of metamizole sodium
Anatomia, Histologia, Embryologia · 2024 SCI-Expanded
Prof. Dr. MUSTAFA ORHUN DAYAN →
YÖKSİS ISSN Eşleşmesi

Bu dergide (ISSN eşleşmesi) kurumun 20 kaydı bulundu.

YÖKSİS Kayıtları — ISSN Eşleşmesi
The Influence of Stomach Volume on the Liver Topography in Cats
2002 ISSN: 0340-2096 SCI 1 atıf
Prof. Dr. EMRULLAH EKEN →
Morphological Studies on Meckel s Diverticulum in Geese Anser Anser Domesticus
2002 ISSN: 0340-2096 SCI 4 atıf
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The Distribution of the Cardiac Veins in Angora Rabbits Oryctolagus cuniculus
2007 ISSN: 0340-2096 SCI 8 atıf
Prof. Dr. SADULLAH BAHAR →
The Distribution of the Coronary Arteries in the Angora Rabbit
2007 ISSN: 0340-2096 SSCI
Prof. Dr. SADULLAH BAHAR →
The Distribution of the Coronary Arteries in the Angora Rabbit
2007 ISSN: 0340-2096 SSCI
Prof. Dr. SADULLAH BAHAR →
Comparison of the Morphometric Features of the Left and Right Horse Kidneys A Stereological Approach
2013 ISSN: 03402096 SSCI
Prof. Dr. SADULLAH BAHAR →
The distribution of the coronary arteries in the angora rabbit
2007 ISSN: 0340-2096 SCI-Expanded 1 atıf
Prof. Dr. SADULLAH BAHAR →
Investigation of Developmental Toxicity and Teratogenicity of Macrolide Antibiotics in Cultured Rat Embryos
2008 ISSN: 03402096 SCI-Expanded
Prof. Dr. ZELİHA FAZLIOĞULLARI →
Investigation of Developmental Toxicity and Teratogenicity of Antiemetics on Rat Embryos Cultured In Vitro
2013 ISSN: 03402096 SCI-Expanded
Prof. Dr. ZELİHA FAZLIOĞULLARI →
Human Fetal Sacral Length Measurement for the Assessment of Fetal Growth and Development by Ultrasonography and Dissection
2001 ISSN: 0340-2096 SCI-Expanded
Prof. Dr. AHMET KAĞAN KARABULUT →
Comparison of the Morphometric Features of the Left and Right Horse Kidneys: A Stereological Approach
2013 ISSN: 03402096 SCI-Expanded Q3
Prof. Dr. SADULLAH BAHAR →
Morphological Studies on Meckel’s Diverticulum in Geese (Anser Anser Domesticus)
2002 ISSN: 0340-2096 SCI
Prof. Dr. KAMİL BEŞOLUK →
Comparative Macroanatomic Investigations of the Venous Drainage of the Heart in Akkaraman Sheep and Angora Goats
2001 ISSN: 0340-2096 SCI
Prof. Dr. KAMİL BEŞOLUK →
A three-dimensional reconstructive study of pelvic cavity in the red fox (Vulpes vulpes)
2021 ISSN: 0340-2096 SCI-Expanded Q3
Prof. Dr. EMRULLAH EKEN →
The Distribution of the Cardiac Veins in Angora Rabbits (Oryctolagus cuniculus)
2007 ISSN: 0340-2096 SCI-Expanded Q3
Prof. Dr. SADULLAH BAHAR →
The distribution of the coronary arteries in the angora rabbit
2007 ISSN: 0340-2096 SCI-Expanded
Prof. Dr. SADULLAH BAHAR →
Comparison of the Morphometric Features of the Left and Right HorseKidneys A Stereological Approach
2013 ISSN: 0340-2096 SCI-Expanded
Prof. Dr. SADULLAH BAHAR →
Morphometric analysis of the skull of Hamdani sheep via Three‐Dimensional modelling
2022 ISSN: 0340-2096 SCI-Expanded Q2
Prof. Dr. MUSTAFA ORHUN DAYAN →
Investigation of Developmental Toxicity and Teratogenicity of Antiemetics on Rat Embryos Cultured title
2013 ISSN: 03402096 SSCI
Prof. Dr. HASAN ACAR →
Calculation of cerebral hemispheres volume values (grey matter, white matter and lateral ventricle) of sheep and goat: A stereological study
2024 ISSN: 0340-2096 SCI-Expanded Q3
Dr. Öğr. Üyesi SEDAT AYDOĞDU →

Makale Bilgileri

Dergi Journal of Veterinary Medicine Series C Anatomia Histologia Embryologia
ISSN03402096
Yayın TarihiEylül 2024
Cilt / Sayfa53
DOI10.1111/ahe.13101
Scopus ID2-s2.0-85201066483
Özet Drug use during pregnancy is an important issue that must be investigated due to its adverse effects on maternal and foetal health. This study aimed to determine the embryotoxic and teratogenic effects of in-ovo administered metamizole (dipyrone), which can be used when needed during pregnancy and has potent analgesic, antipyretic, anti-inflammatory, and long bone (tibia and femur) effects. This study used 240 fertile eggs from Atak S breed chickens, divided into eight equal groups: control, vehicle control, and 15.62, 31.25, 62.5, 125, 250 and 500 mg/kg metamizole. The eggs were hatched on the 21st day of incubation, and the chicks' body weights and mortality rates were determined. The right and left femur and tibia bones were resected from the chicks. Anatomical reference points were determined after removing the soft tissues of the bones, and necessary morphometric measures were taken from these points with a 0.01 mm precision using digital callipers. The 100% lethal dose (LD100) was identified in the highest examined dose (500 mg/kg) in the Chicken Embryotoxicity Screening Test (CHEST)-I stage. The CHEST-II stage determined the 50% lethal dose (LD50). High-dose metamizole affected skeletal development, significantly decreasing tibia and femur lengths and corpus thicknesses and increasing mortality.

Yazarlar (2)

1
Selvinaz Öztürk
ORCID: 0000-0001-8184-6849
2
M. O. Dayan

Anahtar Kelimeler

chicken embryo embryotoxicity LD 50 metamizole teratogenicity

Kurumlar

Selçuk Üniversitesi
Selçuklu Turkey
Scimago Dergi (ISSN Eşleşmesi)
Journal of Veterinary Medicine Series C: Anatomia Histologia Embryologia
Q2
SJR Skoru0,317
H-Index46
YayıncıWiley-Blackwell Publishing Ltd
ÜlkeUnited Kingdom
Veterinary (miscellaneous) (Q2)
Medicine (miscellaneous) (Q3)
Dergi sayfasına git

Metrikler

2
Atıf
2
Yazar
5
Anahtar Kelime

Sistemimizdeki Yazarlar

MD
MUSTAFA ORHUN DAYAN
Prof. Dr.

Hızlı Erişim

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