Scopus
🔓 Açık Erişim
Effects of diode laser application on inflammation and mpo in periodontatissues in a rat model
Journal of Applied Oral Science · Ocak 2018
Makale Bilgileri
DergiJournal of Applied Oral Science
Yayın TarihiOcak 2018
Cilt / Sayfa26
Scopus ID2-s2.0-85050438017
Erişim🔓 Açık Erişim
Özet
Objective: In this study, we aimed to histologically and immunologically evaluate the effect of diode laser treatment when applied adjunctive to scaling and root planing (SRP) in an experimental periodontitis model. Materials and methods: We used Wistar-Albino rats (n=60) with average weight of 230 g. Experimental periodontitis was induced by ligature at the right and left first mandibular molar teeth in all rats. After 11 days, the ligature was removed and rats were divided into two groups. The control group (n=30) received only SRP treatment, while the laser group (n=30) received a diode laser (GaAlAs, 810 nm, 1 W, 10 J, 20 s) treatment adjunctive to SRP. Ten rats in each group were sacrificed after 7, 15, and 30 days. Histopathological examination was performed in the left mandible of rats. Myeloperoxidase (MPO) was evaluated by western blot in the gingival specimens from the right mandible. Results: MPO levels in the laser group were statistically significantly lower compared with the control group (p≤0.05). There was no statistically significance at any time between MPO levels in the control group (p>0.05). MPO levels in the laser group at the 7th day were statistically significantly higher compared to the 15th (p≤0.05) and the 30th day (p≤0.05). Inflammatory cell infiltration decreased over time in both groups and was statistically significantly lower in the laser group than in the control group at all times (p≤0.01). Conclusions: Within the limits of this study, we suggest that diode laser application is an adjunctive treatment because it reduced inflammation and MPO when applied in addition to SRP. On the other hand, more studies are needed for the assessment of the effects of diode laser application to periodontal tissues.
Yazarlar (6)
1
Mustafa Özay Uslu
2
Abubekir Eltas
3
İsmail Marakoğlu
4
Serkan Dündar
5
Kazım Şahin
6
İbrahim Hanifi Özercan
Anahtar Kelimeler
Experimental periodontitis
Inflammation and innate immunity
Laser
Non-surgical periodontal therapy
Kurumlar
Firat Üniversitesi
Elazig Turkey
Firat Üniversitesi Tip Fakültesi
Elazig Turkey
Inönü Üniversitesi
Malatya Turkey
Selçuk Üniversitesi
Selçuklu Turkey
Metrikler
20
Atıf
6
Yazar
4
Anahtar Kelime