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Influences of tolfenamic acid and flunixin meglumine on the disposition kinetics of levofloxacin in sheep

Acta Veterinaria Hungarica · Mart 2020

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YÖKSİS Kayıtları
Influences of tolfenamic acid and flunixin meglumine on the disposition kinetics of levofloxacin in sheep
Acta Veterinaria Hungarica · 2020 SCI-Expanded
Doç. Dr. MERVE İDER →
Influences of tolfenamic acid and flunixin meglumine on the disposition kinetics of levofloxacin in sheep
Acta Veterinaria Hungarica · 2020 SCI-Expanded
Prof. Dr. KAMİL ÜNEY →
YÖKSİS ISSN Eşleşmesi

Bu dergide (ISSN eşleşmesi) kurumun 20 kaydı bulundu.

YÖKSİS Kayıtları — ISSN Eşleşmesi
Zinc supplementation decreases total thyroid hormone concentration in small ruminants
2002 ISSN: 0236-6290 SCI 18 atıf
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Effects of bovine viral diarrhoea virus on the fertility of cows
2013 ISSN: 0236-6290 SSCI
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ASSESSMENT OF THE CARDIOTOXICITY OF TULATHROMYCIN IN RABBITS
2011 ISSN: 0236-6290 SCI-Expanded 37 atıf
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EFFECTS OF ENROFLOXACIN FLUNIXIN MEGLUMINE AND DEXAMETHASONE ONDISSEMINATED INTRAVASCULAR COAGULATION CYTOKINE LEVELS AND ADENOSINEDEAMINASE ACTIVITY IN ENDOTOXAEMIA IN RATS
2010 ISSN: 0236-6290 SCI-Expanded 23 atıf
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EFFECTS OF TYLOSIN ON SERUM CYTOKINE LEVELS IN HEALTHY ANDLIPOPOLYSACCHARIDE TREATED MICE
2010 ISSN: 0236-6290 SCI-Expanded 18 atıf
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Zinc Supplementation Decreases Total Thyroid Hormone Concentration in Small Ruminants
2002 ISSN: 0236-6290 SCI-Expanded
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Cardiac biomarkers in premature calves with respiratory distress syndrome
2016 ISSN: 0236-6290 SCI
Prof. Dr. HASAN GÜZELBEKTEŞ →
Effects of bovine viral diarrhoea virus on the fertility of cows
2013 ISSN: 0236-6290 SCI-Expanded
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Effect of pentoxifylline on endotoxin induced haemostatic disturbances in rabbits
2005 ISSN: 0236-6290 SCI 7 atıf
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Effect of recombinant interleukin 10 on some haematological and biochemical parameters in a rat endotoxaemic model
2011 ISSN: 0236-6290 SCI 6 atıf
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Effects of Arginine and Trehalose on Post-thawed Bovine Sperm Quality
2017 ISSN: 0236-6290 SCI
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Effects of arginine and trehalose on post-thawed bovine sperm quality
2017 ISSN: 0236-6290 SCI
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Plasma disposition of cefoperazone after single intravenous and intramuscular administrations in camels (Camelus dromedarius) )/title
2018 ISSN: 0236-6290 SCI-Expanded
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title Plasma disposition of cefoperazone after single intravenous and intramuscular administrations in camels ( iCamelus dromedarius/i )/title
2018 ISSN: 0236-6290 SCI-Expanded
Prof. Dr. KAMİL ÜNEY →
Assessment of the cardiotoxicity of tulathromycin in rabbits
2011 ISSN: 0236-6290 SSCI
Prof. Dr. ENVER YAZAR →
Effect of pentoxifylline on endotoxin-induced haemostatic, disturbances in rabbits
2005 ISSN: 0236-6290 SCI-Expanded
Prof. Dr. ERCAN KESKİN →
Changes In Novel Gastrointestinal And Renal Injury Markers In The Blood Plasma Of Sheep Following Increasing Intravenous Doses Of Tolfenamic Acid
2019 ISSN: 0236-6290 SCI
Prof. Dr. MAHMUT OK →
Heart-type fatty acid-binding protein (H-FABP), pentraxin-3 (PTX-3) and thrombomodulin in bovine traumatic pericarditis
2019 ISSN: 0236-6290 SCI-Expanded Q3
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CHANGES IN NOVEL GASTROINTESTINAL AND RENAL INJURY MARKERS IN THE BLOOD PLASMA OF SHEEP FOLLOWING INCREASING INTRAVENOUS DOSES OF TOLFENAMIC ACID
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Effects of tylosin, tilmicosin and tulathromycin on inflammatory mediators in bronchoalveolar lavage fluid of lipopolysaccharide-induced lung injury
2012 ISSN: 0236-6290 SCI-Expanded
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Makale Bilgileri

Dergi Acta Veterinaria Hungarica
ISSN02366290
Yayın TarihiMart 2020
Cilt / Sayfa68 · 65-70
DOI10.1556/004.2020.00015
Scopus ID2-s2.0-85086513933
Erişim🔓 Açık Erişim
Özet The pharmacokinetics of levofloxacin (4 mg/kg), administered both alone and in combination with tolfenamic acid (2 mg/kg) and flunixin meglumine (2.2 mg/kg), was established after intravenous administration in sheep. Plasma levofloxacin concentrations were assayed by high-performance liquid chromatography and analysed according to the two-compartment open model. Following the administration of levofloxacin alone, the mean distribution half-life, elimination half-life, total clearance, volume of distribution at steady state and area under the plasma concentration-time curve were 0.20 h, 1.82 h, 0.39 L/h/kg, 0.96 L/kg and 10.40 h 3 mg/mL, respectively. Tolfenamic acid and flunixin meglumine caused a slow elimination and increased plasma concentrations of levofloxacin in combination administration. Levofloxacin, with an alteration in the dosage regimen, can be used effectively with tolfenamic acid and flunixin meglumine for the therapy of infections and inflammatory conditions in sheep.

Yazarlar (7)

1
D. Durna Corum
2
Orhan Corum
ORCID: 0000-0003-3168-2510
3
Ramazan Yildiz
4
Hatice Eser Faki
5
Merve Ider
ORCID: 0000-0003-2928-5452
6
Gul Cetin
7
Kamil Üney
ORCID: 0000-0002-8674-4873

Anahtar Kelimeler

Flunixin meglumine Levofloxacin Pharmacokinetics Sheep Tolfenamic acid

Kurumlar

Burdur Mehmet Akif Ersoy Üniversitesi
Burdur Turkey
Erzincan Binali Yıldırım Üniversitesi
Erzincan Turkey
Kastamonu University
Kastamonu Turkey
Selçuk Üniversitesi
Selçuklu Turkey
Scimago Dergi (ISSN Eşleşmesi)
Acta Veterinaria Hungarica
Q3
SJR Skoru0,281
H-Index42
YayıncıAkademiai Kiado ZRt.
ÜlkeHungary
Veterinary (miscellaneous) (Q3)
Dergi sayfasına git

Metrikler

14
Atıf
7
Yazar
5
Anahtar Kelime

Sistemimizdeki Yazarlar

Mİ
MERVE İDER
Doç. Dr.

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